Role of oncogenes and tumor-suppressor genes in carcinogenesis: a review

EN Kontomanolis, A Koutras, A Syllaios… - Anticancer …, 2020 - ar.iiarjournals.org
Cancer is a medical condition which has a molecular basis. Proto-oncogenes are the first
regulatory factors of this biological process. They act in transmitting signals, resulting as growth …

[HTML][HTML] The notch pathway in breast cancer progression

EN Kontomanolis, S Kalagasidou, S Pouliliou… - The Scientific World …, 2018 - hindawi.com
Objective. Notch signaling pathway is a vital parameter of the mammalian vascular system.
In this review, the authors summarize the current knowledge about the impact of the Notch …

The social stigma of HIV–AIDS: society's role

EN Kontomanolis, S Michalopoulos… - HIV/AIDS-Research …, 2017 - Taylor & Francis
AIDS is a devastating and deadly disease that affects people worldwide and, like all
infections, it comes without warning. Specifically, childbearing women with AIDS face constant …

Vascular endothelial growth factor gene polymorphisms and pre‐eclampsia

…, I Panagopoulos, EN Kontomanolis… - MHR: Basic science …, 2004 - academic.oup.com
Vascular endothelial growth factor (VEGF) plays a crucial role in physiological vasculogenesis
and vascular permeability and has been implicated in the pathogenesis of pre‐eclampsia…

[PDF][PDF] Interleukins associated with breast cancer

…, V Papamanolis, EN Kontomanolis, E Kontomanolis - Cureus, 2018 - cureus.com
A tumor consists of a group of cells with abnormal growth, capable of acquiring unique
characteristics that provide them with the ability to display mercurial migration patterns, adapting …

[HTML][HTML] Intrauterine growth restriction due to gestational diabetes: from pathophysiology to diagnosis and management

…, A Valsamaki, G Daskalakis, EN Kontomanolis - Medicina, 2023 - mdpi.com
Intrauterine growth restriction (IUGR) represents a condition where the fetal weight is less
than the 10th percentile for gestational age, or the estimated fetal weight is lower than …

[HTML][HTML] Pregnancy and COVID-19

…, A Daponte, G Daskalakis, EN Kontomanolis - Journal of Clinical …, 2022 - mdpi.com
Evidence indicates that SARS-CoV-2 infection increases the likelihood of adverse pregnancy
outcomes. Modifications in the circulatory, pulmonary, hormonal, and immunological …

[PDF][PDF] Breast cancer apoptosis and the therapeutic role of luteolin

…, A Pagkalos, T Ntounis, EN Kontomanolis - …, 2021 - revistachirurgia.ro
Breast cancer represents one of the three most common gynecological cancers, with each
subtype having distinct risk profile and treatment strategies. Optimal therapy for each case …

Association of− 634G/C and 936C/T polymorphisms of the vascular endothelial growth factor with spontaneous preterm delivery

…, MI Koukourakis, EN Kontomanolis… - Acta obstetricia et …, 2004 - Taylor & Francis
Background. There is convincing evidence for a central role of vascular endothelial growth
factor (VEGF) in fetal and placental angiogenesis. Our present study was undertaken to …

The relevance of notch signaling in cancer progression

…, K Angelou, D Loutradis, EN Kontomanolis - Notch Signaling in …, 2021 - Springer
The Notch signaling pathway controls normal embryonic development and tissue homeostasis
of many cell types. It regulates cell proliferation, fate, differentiation, and cell death by …