[HTML][HTML] Hemoadsorption in the critically ill—final results of the International CytoSorb Registry

…, D Olboeter, P Muck, M Findeisen, D Bitzinger… - PLoS …, 2022 - journals.plos.org
The aim of the current paper is to summarize the results of the International CytoSorb
Registry. Data were collected on patients of the intensive care unit. The primary endpoint was …

[HTML][HTML] Staurosporine induces apoptosis in pancreatic carcinoma cells PaTu 8988t and Panc-1 via the intrinsic signaling pathway

M Malsy, D Bitzinger, B Graf, A Bundscherer - European Journal of …, 2019 - Springer
Background Cancer, one of the leading causes of death worldwide, develops when the
normal balance between mitosis and apoptosis is disrupted. The subsequently increased …

Relevance of peripheral cholinesterase activity on postoperative delirium in adult surgical patients (CESARO): A prospective observational cohort study

…, K Plaschke, V von Dossow, D Bitzinger… - European Journal of …, 2019 - journals.lww.com
BACKGROUND The cholinergic system is considered to play a key role in the development
of postoperative delirium (POD), which is a common complication after surgery. …

[HTML][HTML] In vivo effects of neostigmine and physostigmine on neutrophil functions and evaluation of acetylcholinesterase and butyrylcholinesterase as inflammatory …

DI Bitzinger, M Gruber, S Tümmler, M Malsy… - Mediators of …, 2019 - hindawi.com
Introduction. Recent studies have shown that acetylcholinesterase (AChE) and butyrylcholinesterase
(BChE) may serve as important diagnostic and therapeutic targets in sepsis. Since …

Effects of lidocaine on HT-29 and SW480 colon cancer cells in vitro

AC Bundscherer, M Malsy, DI Bitzinger… - Anticancer …, 2017 - ar.iiarjournals.org
Background: Evidence is growing that the risk of cancer dissemination may be enhanced
during the perioperative period. Whether particular anesthetic techniques influence …

Butyrylcholinesterase as a perioperative complication marker in patients after transcatheter aortic valve implantation: a prospective observational study

…, W Petermichl, A Müller, YA Zausig, DI Bitzinger - BMJ open, 2021 - bmjopen.bmj.com
Objectives Transcatheter aortic valve implantation (TAVI) is performed in elderly patients with
severe aortic valve stenosis and increased operative risks. We tested the hypothesis that …

[HTML][HTML] The Effect of Local Anesthetics on Neutrophils in the Context of Different Isolation Techniques

S Sixt, M Gruber, G Kolle, T Galla, D Bitzinger - Biomedicines, 2023 - mdpi.com
Various functions of polymorphonuclear neutrophils (PMNs) are related to diseases and
postoperative plasma changes. The influence of some local anesthetics (LAs) on PMNs …

[HTML][HTML] The impact of crystalloidal and colloidal infusion preparations on coronary vascular integrity, interstitial oedema and cardiac performance in isolated hearts

…, D Potschka, H Busse, K Nixdorf, D Bitzinger… - Critical Care, 2013 - Springer
Introduction Recent data suggested an interaction between plasma constituents and the
endothelial glycocalyx to be relevant for vascular barrier function. This might be negatively …

[HTML][HTML] Adenosine A2A and A2B receptor substantially attenuate ischemia/reperfusion injury in septic rat hearts

H Busse, D Bitzinger, K Höcherl, T Seyfried… - … drugs and therapy, 2016 - Springer
Introduction Mechanical and morphological ischemia and reperfusion (I/R) injury is reduced
in septic hearts. The mechanism behind this “cardioprotection” is less well understood. As …

[HTML][HTML] Therapeutic anticoagulation with argatroban and heparins reduces granulocyte migration: possible impact on ECLS-therapy?

…, W Petermichl, T Seyfried, D Bitzinger… - Cardiovascular …, 2020 - hindawi.com
Introduction. Anticoagulants such as argatroban and heparins (low-molecular-weight and
unfractionated) play an immense role in preventing thromboembolic complications in clinical …