Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer?

…, A Orlandi, A Strippoli, AM Ferrara, C Bagalą… - Clinical colorectal …, 2011 - Elsevier
Background The KRAS mutation is not responsible for all cases of resistance to anti–epidermal
growth factor receptors (EGFRs) in metastatic colorectal cancer (mCRC), and new …

The non-classical export routes: FGF1 and IL-1α point the way

…, A Mandinova, R Soldi, C Bagala… - Journal of cell …, 2003 - journals.biologists.com
Non-classical protein release independent of the ER-Golgi pathway has been reported for
an increasing number of proteins lacking an N-terminal signal sequence. The export of FGF1 …

Reverse Transcriptase Inhibitors Down-Regulate Cell Proliferation in Vitro and in Vivo and Restore Thyrotropin Signaling and Iodine Uptake in Human Thyroid …

…, A Fabiano, S Altamura, C Bagalą… - The Journal of …, 2005 - academic.oup.com
Context: Two classes of repeated genomic elements, retrotransposons and endogenous
retroviruses, encode for endogenous nontelomeric reverse transcriptase (RT), a gene that is …

Copper chelation represses the vascular response to injury

…, V Kolev, R Soldi, C Bagala… - Proceedings of the …, 2003 - National Acad Sciences
The induction of an acute inflammatory response followed by the release of polypeptide
cytokines and growth factors from peripheral blood monocytes has been implicated in mediating …

[HTML][HTML] Copper induces the assembly of a multiprotein aggregate implicated in the release of fibroblast growth factor 1 in response to stress

M Landriscina, C Bagalį, A Mandinova, R Soldi… - Journal of Biological …, 2001 - ASBMB
Fibroblast growth factor (FGF) 1 is known to be released in response to stress conditions as
a component of a multiprotein aggregate containing the p40 extravescicular domain of p65 …

The intracellular translocation of the components of the fibroblast growth factor 1 release complex precedes their assembly prior to export

I Prudovsky, C Bagala, F Tarantini… - The Journal of cell …, 2002 - rupress.org
The release of signal peptideless proteins occurs through nonclassical export pathways
and the release of fibroblast growth factor (FGF)1 in response to cellular stress is well …

Pressurized intraperitoneal aerosol chemotherapy with cisplatin and doxorubicin or oxaliplatin for peritoneal metastasis from pancreatic adenocarcinoma and …

…, S Rotolo, CA Schena, C Bagalą… - Therapeutic …, 2020 - journals.sagepub.com
Background: Systemic chemotherapy for pancreatic adenocarcinoma (PDAC) and
cholangiocarcinoma (CC) with peritoneal metastases (PM) is affected by several pharmacological …

S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells

…, R Soldi, I Graziani, C Bagalį… - Journal of cell …, 2003 - journals.biologists.com
Copper is involved in the promotion of angiogenic and inflammatory events in vivo and,
although recent clinical data has demonstrated the potential of Cu 2+ chelators for the treatment …

[HTML][HTML] S100A13 participates in the release of fibroblast growth factor 1 in response to heat shock in vitro

M Landriscina, R Soldi, C Bagalį, I Micucci… - Journal of Biological …, 2001 - ASBMB
S100A13, a member of the S100 gene family of Ca 2+ -binding proteins has been previously
characterized as a component of a brain-derived heparin-binding multiprotein aggregate/…

Expression of vascular endothelial growth factor, mitogen-activated protein kinase and p53 in human colorectal cancer.

A Cassano, C Bagalą, C Battelli, G Schinzari… - Anticancer …, 2002 - europepmc.org
Background VEGF is a growth factor involved in the regulation of angiogenesis, a process
that plays a central role in tumor growth. It has been suggested that mutations of p53 and …