Zinc is present in presynaptic nerve terminals throughout the mammalian central nervous
system and likely serves as an endogenous signaling substance. However, excessive …

Cell death was examined by studying the spinal cords of rats subjected to traumatic insults
of mild to moderate severity. Within minutes after mild weight drop impact (a 10 gm weight …

Background Limited data are available to guide the choice of a target for the systolic blood-pressure
level when treating acute hypertensive response in patients with intracerebral …

Infarct volume is one of the common indexes for assessing the extent of ischemic brain
injury following focal cerebral ischemia. Accuracy in the measurement of infarct volume is …

In the search for a more reproducible focal ischemic stroke model in the rat, we systematically
interrupted blood flow to the right middle cerebral artery territory by ligating the right middle …

The temporal evolution of cerebral infarction was examined in rats subjected to transient
occlusion of both common carotid arteries and the right middle cerebral artery. After severe (90-…

… HOGAN, AND CHUNG Y. Hsu. Polyethylene glycolconjugated superoxide dismutase
and catalase reduce ischemic brain injury. Am. … CY Hsu is a recipient of a NINCDS …

The pathological hallmark of Alzheimer disease is the senile plaque principally composed
of tightly aggregated amyloid-β fibrils (fAβ), which are thought to be resistant to degradation …

It has been postulated that the development of amyloid plaques in Alzheimer's disease (AD)
may result from an imbalance between the generation and clearance of the amyloid-β …

Background and purpose On 11 March 2020, World Health Organization (WHO) declared the
COVID-19 infection a pandemic. The risk of ischemic stroke may be higher in patients with …