Soluble form of the (pro) renin receptor generated by intracellular cleavage by furin is secreted in plasma

C Cousin, D Bracquart, A Contrepas, P Corvol… - …, 2009 - Am Heart Assoc
The (pro)renin receptor [(P)RR] is a 35-kDa transmembrane protein that plays a pivotal role
in angiotensin tissue generation and in nonproteolytic prorenin activation. We detected a …

[PDF][PDF] Potential role of the (pro) renin receptor in cardiovascular and kidney diseases

C Cousin, D Bracquart, A Contrepas… - JN journal of …, 2010 - researchgate.net
The discovery of a (pro) renin receptor ((P) RR) and the introduction of renin inhibitors in the
clinic has brought prorenin, the inactive proenzyme form of renin, back into the spotlight. …

Clinical relevance of routine monitoring of patient-reported outcomes versus clinician-reported outcomes in oncology

F Fiteni, A Cuenant, M Favier, C Cousin, N Houédé - in vivo, 2019 - iv.iiarjournals.org
The National Cancer Institute Common Terminology Criteria for Adverse Events classification
is the standard classification used by the physicians in oncology for reporting adverse …

A simple blood test expedites the diagnosis of glucose transporter type 1 deficiency syndrome

D Gras, C Cousin, C Kappeler, CW Fung… - Annals of …, 2017 - Wiley Online Library
Glucose transporter type 1 (GLUT1) deficiency syndrome (GLUT1‐DS) leads to a wide
range of neurological symptoms. Ketogenic diets are very efficient to control epilepsy and …

Cytostatic effect of repeated exposure to simvastatin: a mechanism for chronic myotoxicity revealed by the use of mesodermal progenitors derived from human …

…, AL Egesipe, L Meyniel-Schicklin, C Cousin… - Stem Cells, 2015 - academic.oup.com
Statin treatment of hypercholesterolemia can lead to chronic myotoxicity which is, in most
cases, alleviated by drug withdrawal. Cellular and molecular mechanisms of this adverse effect …

The prorenin receptor

D Bracquart, C Cousin, A Contrepas… - Journal de la Societe de …, 2009 - europepmc.org
The renin-angiotensin system (RAS) is one of the most important systems in physiology and
in pathology. The (pro) renin receptor [(P) RR] is a new component of the system that has …

Chimiothérapies dans le cancer colorectal: étude pragmatique des modifications de prescription et de dose intensité

…, V Loriot, V Phouttasang, P Wolf, S Bastide, C Cousin… - Bulletin du …, 2017 - Elsevier
Introduction Les toxicités induites par les chimiothérapies peuvent générer des modifications
de prescription et de dose intensité relative, ayant un impact sur l’efficacité thérapeutique. …

Chemotherapy for colorectal cancer: Pragmatic assessment of prescription changes and relative dose intensity

…, V Phouttasang, P Wolf, S Bastide, C Cousin… - Bulletin du …, 2017 - europepmc.org
Method This is a prospective observational study performed in hepato-gastroenterology
department for 6 months. All patients treated for colorectal cancer and beginning a protocol with …

Élaboration d'un guide standardisé d'informations d'optimisation de l'adhésion médicamenteuse à dispenser lors d'une consultation pharmaceutique au patient atteint …

C Favier-Archinard, G Leguelinel-Blache, C Cousin… - Bulletin du …, 2018 - Elsevier
Une validation initiale d’un guide de consultation pharmaceutique standardisé a été
réalisée dans un précédent travail pour optimiser l’adhésion médicamenteuse du patient au …

[HTML][HTML] Association between GLUT1 and HbF levels in red blood cells from patients with sickle cell disease

A Paikari, A Goyal, C Cousin, V Petit, VA Sheehan - Blood, 2019 - Elsevier
Background: Glucose transporter 1 (GLUT1) is a ubiquitously expressed protein highly
expressed on the surface of erythrocytes. As a member of insulin signaling pathway, GLUT1 is …