[HTML][HTML] TGF-β induced EMT and stemness characteristics are associated with epigenetic regulation in lung cancer

…, SH Lee, MS Park, HW Yim, JY Park, CK Park… - Scientific Reports, 2020 - nature.com
Transforming growth factor-β (TGF-β) promotes tumor invasion and metastasis by inducing
epithelial-mesenchymal transition (EMT). EMT is often related with acquisition of stemness …

[HTML][HTML] The role of hypoxia on the acquisition of epithelial-mesenchymal transition and cancer stemness: a possible link to epigenetic regulation

…, N Kang, SY Choi, BN Kim, CK Park… - The Korean journal of …, 2017 - ncbi.nlm.nih.gov
A hypoxic microenvironment leads to cancer progression and increases the metastatic
potential of cancer cells within tumors via epithelial-mesenchymal transition (EMT) and cancer …

Effect of tiotropium bromide on airway remodeling in a chronic asthma model

…, CK Park, SJ Kim, SH Lee, HK Yoon, SS Kwon… - Annals of Allergy …, 2012 - Elsevier
BACKGROUND: Recent evidence suggests that acetylcholine acting through muscarinic
receptors may play an inhibitory role in the mechanisms that drive the structural changes in the …

Detection and comparison of EGFR mutations in matched tumor tissues, cell blocks, pleural effusions, and sera from patients with NSCLC with malignant pleural …

…, CK Rhee, SJ Kim, YK Kim, CK Park, SH Lee, MS Park… - Lung cancer, 2013 - Elsevier
Peptide nucleic acid (PNA)-mediated real-time PCR clamping has higher sensitivity than
conventional direct sequencing for detecting mutations. Pleural effusion and serum may …

Expression of insulin-like growth factor 1 receptor (IGF-1R) predicts poor responses to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small …

CD Yeo, KH Park, CK Park, SH Lee, SJ Kim, HK Yoon… - Lung cancer, 2015 - Elsevier
Objectives Expression of insulin-like growth factor 1 receptor (IGF-1R) in non-small cell lung
cancer (NSCLC) is associated with poor prognosis. The IGF-1R pathway activates …

PD‐L1 expression in ROS1‐rearranged non‐small cell lung cancer: A study using simultaneous genotypic screening of EGFR, ALK, and ROS1

J Lee, CK Park, HK Yoon, YJ Sa, IS Woo… - Thoracic …, 2019 - Wiley Online Library
Background The aim of the current study was to investigate the prevalence and clinicopathologic
characteristics of ROS1‐rearranged non‐small cell lung cancer (NSCLC) in routine …

Effect of imatinib on airway smooth muscle thickening in a murine model of chronic asthma

…, SJ Kim, SC Kim, SS Kwon, YK Kim, SH Park… - International archives of …, 2011 - karger.com
Background: Asthma is characterized by airway hyperresponsiveness (AHR), inflammation
and remodeling. The tyrosine kinase inhibitor imatinib mesylate was developed to inhibit BCR…

[HTML][HTML] Prognostic value of platelet count and lymphocyte to monocyte ratio combination in stage IV non-small cell lung cancer with malignant pleural effusion

JU Lim, CD Yeo, HS Kang, CK Park, JS Kim, JW Kim… - PloS one, 2018 - journals.plos.org
Introduction A combination of platelet and lymphocyte to monocyte ratio (LMR) (abbreviated
as COP-LMR) has been recently evaluated as systemic inflammatory marker for …

[HTML][HTML] Effects of macrolide and corticosteroid in neutrophilic asthma mouse model

…, JH Kim, YR Lee, JY Chon, CK Park… - Tuberculosis and …, 2018 - ncbi.nlm.nih.gov
Background Asthma is a disease of chronic airway inflammation with heterogeneous
features. Neutrophilic asthma is corticosteroid-insensitive asthma related to absence or …

[HTML][HTML] Final Report on Real-World Effectiveness of Sequential Afatinib and Osimertinib in EGFR-Positive Advanced Non–Small Cell Lung Cancer: Updated Analysis …

…, JS Ryu, JE Lee, SY Lee, CK Park… - Cancer Research and …, 2023 - ncbi.nlm.nih.gov
Purpose This study aimed to report the final analysis of time-on-treatment (TOT) and overall
survival (OS) in patients with advanced-stage epidermal growth factor receptor (EGFR)+ non…