User profiles for CHAEUK CHUNG

Chaeuk Chung

Chungnam National University
Verified email at cnuh.co.kr
Cited by 2479

Hippo effector YAP directly regulates the expression of PD-L1 transcripts in EGFR-TKI-resistant lung adenocarcinoma

…, SS Jung, JO Kim, SY Cho, HS Park, C Chung - Biochemical and …, 2017 - Elsevier
Developments of EGFR-TKI and immunotherapy targeting the PD1/PD-L1 pathway are
considered most important medical breakthroughs in lung cancer treatment. Nowadays, 3rd …

[HTML][HTML] Respiratory sound classification for crackles, wheezes, and rhonchi in the clinical field using deep learning

Y Kim, YK Hyon, SS Jung, S Lee, G Yoo, C Chung… - Scientific reports, 2021 - nature.com
Auscultation has been essential part of the physical examination; this is non-invasive, real-time,
and very informative. Detection of abnormal respiratory sounds with a stethoscope is …

[HTML][HTML] Baseline serum interleukin-6 levels predict the response of patients with advanced non-small cell lung cancer to PD-1/PD-L1 inhibitors

CK Park, C Chung, IJ Oh, YC Kim, D Park, J Kim… - Immune …, 2020 - ncbi.nlm.nih.gov
Although various studies on predictive markers in the use of PD-1/PD-L1 inhibitors are in
progress, only PD-L1 expression levels in tumor tissues are currently used. In the present study…

[HTML][HTML] Vitamin D-cathelicidin axis: at the crossroads between protective immunity and pathological inflammation during infection

C Chung, P Silwal, I Kim, RL Modlin, EK Jo - Immune network, 2020 - ncbi.nlm.nih.gov
Vitamin D signaling plays an essential role in innate defense against intracellular
microorganisms via the generation of the antimicrobial protein cathelicidin. In addition to directly …

Autophagy: A new strategy for host-directed therapy of tuberculosis

S Paik, JK Kim, C Chung, EK Jo - Virulence, 2019 - Taylor & Francis
Tuberculosis (TB), which is primarily caused by the major etiologic agent Mycobacterium
tuberculosis (Mtb), remains a serious infectious disease worldwide. Recently, much effort has …

[HTML][HTML] Crosstalks between inflammasome and autophagy in cancer

C Chung, W Seo, P Silwal, EK Jo - Journal of hematology & oncology, 2020 - Springer
Both inflammasomes and autophagy have important roles in the intracellular homeostasis,
inflammation, and pathology; the dysregulation of these processes is often associated with …

[HTML][HTML] New insights into the clinical implications of yes-associated protein in lung cancer: roles in drug resistance, tumor immunity, autophagy, and organoid …

G Yoo, D Park, Y Kim, C Chung - Cancers, 2021 - mdpi.com
Simple Summary Innovative advancements in lung cancer treatment have developed over
the past decade with the advent of targeted and immune therapies. Yes-associated protein (…

[HTML][HTML] Yap-and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development

…, A Gregorieff, M Bagherie-Lachidan, C Chung… - PLoS …, 2013 - journals.plos.org
Yap is a transcriptional co-activator that regulates cell proliferation and apoptosis
downstream of the Hippo kinase pathway. We investigated Yap function during mouse kidney …

Fully portable continuous real-time auscultation with a soft wearable stethoscope designed for automated disease diagnosis

…, MK Yeo, M Mahmood, N Zavanelli, C Chung… - Science …, 2022 - science.org
Modern auscultation, using digital stethoscopes, provides a better solution than conventional
methods in sound recording and visualization. However, current digital stethoscopes are …

[HTML][HTML] COVID-19 patients upregulate toll-like receptor 4-mediated inflammatory signaling that mimics bacterial sepsis

…, IS Kim, P Silwal, YJ Kim, S Paik, C Chung… - Journal of Korean …, 2020 - ncbi.nlm.nih.gov
Background Observational studies of the ongoing coronavirus disease 2019 (COVID-19)
outbreak suggest that a ‘cytokine storm’is involved in the pathogenesis of severe illness. …