User profiles for CHAEUK CHUNG
Chaeuk ChungChungnam National University Verified email at cnuh.co.kr Cited by 2479 |
Hippo effector YAP directly regulates the expression of PD-L1 transcripts in EGFR-TKI-resistant lung adenocarcinoma
Developments of EGFR-TKI and immunotherapy targeting the PD1/PD-L1 pathway are
considered most important medical breakthroughs in lung cancer treatment. Nowadays, 3rd …
considered most important medical breakthroughs in lung cancer treatment. Nowadays, 3rd …
[HTML][HTML] Respiratory sound classification for crackles, wheezes, and rhonchi in the clinical field using deep learning
Auscultation has been essential part of the physical examination; this is non-invasive, real-time,
and very informative. Detection of abnormal respiratory sounds with a stethoscope is …
and very informative. Detection of abnormal respiratory sounds with a stethoscope is …
[HTML][HTML] Baseline serum interleukin-6 levels predict the response of patients with advanced non-small cell lung cancer to PD-1/PD-L1 inhibitors
Although various studies on predictive markers in the use of PD-1/PD-L1 inhibitors are in
progress, only PD-L1 expression levels in tumor tissues are currently used. In the present study…
progress, only PD-L1 expression levels in tumor tissues are currently used. In the present study…
[HTML][HTML] Vitamin D-cathelicidin axis: at the crossroads between protective immunity and pathological inflammation during infection
Vitamin D signaling plays an essential role in innate defense against intracellular
microorganisms via the generation of the antimicrobial protein cathelicidin. In addition to directly …
microorganisms via the generation of the antimicrobial protein cathelicidin. In addition to directly …
Autophagy: A new strategy for host-directed therapy of tuberculosis
Tuberculosis (TB), which is primarily caused by the major etiologic agent Mycobacterium
tuberculosis (Mtb), remains a serious infectious disease worldwide. Recently, much effort has …
tuberculosis (Mtb), remains a serious infectious disease worldwide. Recently, much effort has …
[HTML][HTML] Crosstalks between inflammasome and autophagy in cancer
Both inflammasomes and autophagy have important roles in the intracellular homeostasis,
inflammation, and pathology; the dysregulation of these processes is often associated with …
inflammation, and pathology; the dysregulation of these processes is often associated with …
[HTML][HTML] New insights into the clinical implications of yes-associated protein in lung cancer: roles in drug resistance, tumor immunity, autophagy, and organoid …
G Yoo, D Park, Y Kim, C Chung - Cancers, 2021 - mdpi.com
Simple Summary Innovative advancements in lung cancer treatment have developed over
the past decade with the advent of targeted and immune therapies. Yes-associated protein (…
the past decade with the advent of targeted and immune therapies. Yes-associated protein (…
[HTML][HTML] Yap-and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development
…, A Gregorieff, M Bagherie-Lachidan, C Chung… - PLoS …, 2013 - journals.plos.org
Yap is a transcriptional co-activator that regulates cell proliferation and apoptosis
downstream of the Hippo kinase pathway. We investigated Yap function during mouse kidney …
downstream of the Hippo kinase pathway. We investigated Yap function during mouse kidney …
Fully portable continuous real-time auscultation with a soft wearable stethoscope designed for automated disease diagnosis
Modern auscultation, using digital stethoscopes, provides a better solution than conventional
methods in sound recording and visualization. However, current digital stethoscopes are …
methods in sound recording and visualization. However, current digital stethoscopes are …
[HTML][HTML] COVID-19 patients upregulate toll-like receptor 4-mediated inflammatory signaling that mimics bacterial sepsis
Background Observational studies of the ongoing coronavirus disease 2019 (COVID-19)
outbreak suggest that a ‘cytokine storm’is involved in the pathogenesis of severe illness. …
outbreak suggest that a ‘cytokine storm’is involved in the pathogenesis of severe illness. …