Distribution patterns of BK polyomavirus (BKV) subtypes and subgroups in American, European and Asian populations suggest co-migration of BKV and the human …

…, M Suzuki, T Takeuchi, A Shibuya… - Journal of General …, 2009 - microbiologyresearch.org
BK polyomavirus (BKV) is ubiquitous in the human population, infecting children asymptomatically
and then persisting in the kidney. Based on serological and genotyping methods, …

Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related multistage hepatocarcinogenesis: comparison with hepatitis virus-related …

…, Y Nozaki, Y Takahashi, N Ito, A Shibuya… - …, 2017 - academic.oup.com
The aim of this study was to clarify the significance of DNA methylation alterations during
non-alcoholic steatohepatitis (NASH)-related hepatocarcinogenesis. Single-CpG-resolution …

The Japanese Society of Pathology Guidelines on the handling of pathological tissue samples for genomic research: standard operating procedures based on …

…, J Kuramoto, E Arai, H Ojima, A Shibuya… - Pathology …, 2018 - Wiley Online Library
Genome research using appropriately collected pathological tissue samples is expected to
yield breakthroughs in the development of biomarkers and identification of therapeutic …

[HTML][HTML] Impact of fatty acids on human UDP-glucuronosyltransferase 1A1 activity and its expression in neonatal hyperbilirubinemia

A Shibuya, T Itoh, RH Tukey, R Fujiwara - Scientific reports, 2013 - nature.com
While breast milk has been known as a cause of neonatal hyperbilirubinemia, the underlying
mechanism of breast milk-induced jaundice has not been clarified. Here, the impact of fatty …

Establishment of permutation for cancer risk estimation in the urothelium based on genome-wide DNA methylation analysis

K Tsumura, E Arai, Y Tian, A Shibuya… - …, 2019 - academic.oup.com
The aim of this study was to establish permutation for cancer risk estimation in the urothelium.
Twenty-six samples of normal control urothelium obtained from patients without urothelial …

Does the placement of a cystic duct tube after a hepatic resection help reduce the incidence of post‐operative bile leak?

A Nanashima, T Abo, A Shibuya, T Tominaga… - HPB, 2013 - Wiley Online Library
Background In this retrospective study, the effects of cystic duct ( C ) tube use on the incidence
of post‐hepatectomy bile leak were assessed. Methods The subjects were 550 patients …

[HTML][HTML] Transcriptional control region rearrangements associated with the evolution of JC polyomavirus

Y Yogo, S Zhong, A Shibuya, T Kitamura, Y Homma - Virology, 2008 - Elsevier
JC polyomavirus (JCV) isolates worldwide are classified into three super-lineages (A, B and
C), with A and B further split into several lineages and sub-lineages. The transcriptional …

Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: a single-institutional methylome analysis using …

K Ohara, E Arai, Y Takahashi, N Ito, A Shibuya… - …, 2017 - academic.oup.com
The aim of this study was to clarify the significance of DNA methylation alterations shared by
cancers derived from multiple organs. We analyzed single-institutional methylome data by …

[HTML][HTML] Short-and long-term survival after curative resection for colorectal cancer in nonagenarian patients

…, M Araki, K Wakata, T Kugiyama, A Shibuya… - Asian Journal of …, 2022 - Elsevier
Background/objective With increased life expectancy, the incidence of colorectal cancer in
oldest-old patients has been rising. Advanced age is a risk factor for adverse outcomes after …

Conserved archetypal configuration of the transcriptional control region during the course of BK polyomavirus evolution

…, C Sugimoto, H Ikegaya, A Shibuya… - Journal of general …, 2008 - microbiologyresearch.org
BK polyomavirus (BKV) is widespread among humans, asymptomatically infecting children
and then persisting in renal tissue. The transcriptional control region (TCR) of the BKV …