Clinical and pathological significance of the level and extent of capsular invasion in clinical stage T1–2 prostate cancer

TM Wheeler, Ö Dillioglugil, MW Kattan, A Arakawa… - Human pathology, 1998 - Elsevier
This study was performed to assess the relationship between the level and extent of prostatic
capsular invasion (PCI) by cancer and the clinical and pathological features and prognosis …

Abnormality of autophagic function and cathepsin expression in the liver from patients with non‐alcoholic fatty liver disease

…, S Yamashina, H Sonoue, A Arakawa… - Hepatology …, 2014 - Wiley Online Library
Aim Recent evidences indicate that hepatic steatosis suppresses autophagic proteolysis.
The present study evaluated the correlation between autophagic function and cathepsin …

[HTML][HTML] Bacteroidetes species are correlated with disease activity in ulcerative colitis

…, S Ito, K Haga, M Takahashi, A Arakawa… - Journal of clinical …, 2021 - mdpi.com
Fecal microbiota transplantation following triple-antibiotic therapy (amoxicillin/fosfomycin/metronidazole)
improves dysbiosis caused by reduced Bacteroidetes diversity in patients with …

The role of cathepsin B and cystatin C in the mechanisms of invasion by ovarian cancer

…, T Nakanishi, K Blomgren, T Tada, A Arakawa… - Gynecologic …, 2004 - Elsevier
Objective. The aim of this study was to investigate the contribution of cathepsin B and cystatin
C to the mechanisms of invasion by ovarian cancer. Materials and methods. Using surgical …

Histological assessment of impact of ovarian endometrioma and laparoscopic cystectomy on ovarian reserve

M Kuroda, K Kuroda, A Arakawa… - Journal of Obstetrics …, 2012 - Wiley Online Library
Aim: The rate of oocyte decline follows a biphasic pattern, characterized by acceleration
between 32 and 38 years old. Ovarian reserve is also affected by external factors, including …

Phase IIa clinical study of [18F]fluciclovine: efficacy and safety of a new PET tracer for brain tumors

…, K Kubota, R Minamimoto, A Arakawa… - Annals of nuclear …, 2016 - Springer
Objective [ 18 F]Fluciclovine (anti-[ 18 F]FACBC) has demonstrated diagnostic efficacy for
cancers of the brain where [ 18 F]fludeoxyglucose has limitations. We conducted a phase IIa …

Aberrant expression of tumor suppressors CADM1 and 4.1 B in invasive lesions of primary breast cancer

Y Takahashi, M Iwai, T Kawai, A Arakawa, T Ito… - Breast cancer, 2012 - Springer
Background The tumor suppressor genes CADM1/TSLC1 and DAL-1/4.1B are frequently
inactivated by promoter methylation in non-small cell lung cancer. The proteins they encode, …

[HTML][HTML] Combination of cancer stem cell markers CD44 and CD24 is superior to ALDH1 as a prognostic indicator in breast cancer patients with distant metastases

Y Horimoto, A Arakawa, N Sasahara, M Tanabe, S Sai… - PloS one, 2016 - journals.plos.org
The combination of CD44 and CD24, or aldehyde dehydrogenase 1 (ALDH1) alone, is a
widely used cancer stem cell marker in breast cancer. However, no conclusion has yet been …

Microsatellite instability and mismatch repair protein expressions in lymphocyte‐predominant breast cancer

…, R Sasaki, A Kurisaki‐Arakawa, A Arakawa… - Cancer …, 2020 - Wiley Online Library
The frequency of microsatellite instability (MSI) is reportedly extremely low in breast cancer,
despite widespread clinical expectations that many patients would be responsive to immune‐…

[HTML][HTML] Bevacizumab combined with platinum–taxane chemotherapy as first-line treatment for advanced ovarian cancer: a prospective observational study of safety …

…, A Hongo, M Asai-Sato, A Arakawa… - International journal of …, 2019 - Springer
Background This was the first large-scale prospective observational Japanese study
evaluating the safety and efficacy of bevacizumab combined with paclitaxel and carboplatin for …