Foxp3-expressing CD25 + CD4 + regulatory T cells (Tregs) are abundant in tumor tissues.
Here, hypothesizing that tumor Tregs would clonally expand after they are activated by tumor-…

Bladder cancer is the most common cancer of the urinary tract. Although nonmuscle-invasive
bladder cancers have a good prognosis, muscle-invasive bladder cancers promote …

OBJECTIVE• To evaluate tumour-associated macrophage (TAM) infiltration in prostate biopsy
specimens as a possible prognostic factor for prostate cancer (PCa) after hormonal therapy…

These results suggest that intestinal bacteria, acting through short-chain fatty acids, regulate
systemic and local prostate IGF1 in the host, which can promote proliferation of prostate …

Extracellular vesicles (EVs) are microvesicles secreted from various cell types. We aimed to
discover a new biomarker for high Gleason score (GS) prostate cancer (PCa) in urinary EVs …

Purpose: High-fat diet (HFD) could induce prostate cancer progression. The aim of this
study is to identify mechanisms of HFD-induced prostate cancer progression, focusing on …

This article is an English translation of the Clinical Practice Guidelines for Upper Tract
Urothelial Carcinoma (2nd edition) published in June 2023. The Japanese Urological …

Regulatory T cells (Tregs) have an immunosuppressive role in the tumor microenvironment.
Since effector Tregs (eTregs), which have highly suppressive functions, are located in a …

Methods This narrative review summarized the subgroup analyses of clinical trials of FDA-approved
targeted drugs to explore the differential effects of each targeted drug when …

Purpose To present mature results of high-dose-rate brachytherapy (HDR-BT) as monotherapy
for intermediate- and high-risk prostate cancer. Methods and Materials From 1995 …