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A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer.
Cevatemre B, Erkısa M, Aztopal N, Karakas D, Alper P, Tsimplouli C, Sereti E, Dimas K, Armutak EII, Gurevin EG, Uvez A, Mori M, Berardozzi S, Ingallina C, D'Acquarica I, Botta B, Ozpolat B, Ulukaya E. Cevatemre B, et al. Among authors: gurevin eg. Pharmacol Res. 2018 Mar;129:500-514. doi: 10.1016/j.phrs.2017.11.027. Epub 2017 Dec 6. Pharmacol Res. 2018. PMID: 29197639
The effect of high mobility group box-1 protein on cerebral edema, blood-brain barrier, oxidative stress and apoptosis in an experimental traumatic brain injury model.
Evran S, Calis F, Akkaya E, Baran O, Cevik S, Katar S, Gurevin EG, Hanimoglu H, Hatiboglu MA, Armutak EI, Karatas E, Kocyigit A, Kaynar MY. Evran S, et al. Among authors: gurevin eg. Brain Res Bull. 2020 Jan;154:68-80. doi: 10.1016/j.brainresbull.2019.10.013. Epub 2019 Nov 9. Brain Res Bull. 2020. PMID: 31715313