Abstract
Omeprazole is a proton pump inhibitor widely used for the treatment of peptic ulcer disease. We report a patient presenting nonoliguric acute renal failure following omeprazole treatment. Both eosinophilia and eosinophiluria were observed, and the patient was diagnosed as having drug-induced acute interstitial nephritis. Renal failure spontaneously resolved when omeprazole was discontinued.
MeSH terms
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Acute Disease
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Aged
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Anti-Ulcer Agents / adverse effects*
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Biopsy
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Blood Urea Nitrogen
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Creatinine / blood
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Duodenal Ulcer / complications
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Duodenal Ulcer / drug therapy
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Female
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Follow-Up Studies
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Humans
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Nephritis, Interstitial / blood
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Nephritis, Interstitial / chemically induced*
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Nephritis, Interstitial / pathology
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Omeprazole / adverse effects*
Substances
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Anti-Ulcer Agents
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Creatinine
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Omeprazole