Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion

Biochem Biophys Res Commun. 1981 Jul 30;101(2):440-6. doi: 10.1016/0006-291x(81)91279-1.
No abstract available

MeSH terms

  • Arginine / analogs & derivatives
  • Binding Sites
  • Kinetics
  • Methods
  • Optical Rotation
  • Pipecolic Acids / chemical synthesis
  • Pipecolic Acids / pharmacology*
  • Stereoisomerism
  • Sulfonamides
  • Thrombin / antagonists & inhibitors*

Substances

  • Pipecolic Acids
  • Sulfonamides
  • Arginine
  • Thrombin
  • argatroban