Biopsy of the scalene fat pad in carcinoma of the cervix uteri metastatic to the periaortic lymph nodes

Surg Gynecol Obstet. 1987 Dec;165(6):503-6.

Abstract

Fifty-five patients with squamous cell carcinoma of the cervix uteri metastatic to high common iliac or periaortic lymph nodes underwent biopsy of the left scalene fat pad as part of a prospective clinical trial. Patients without metastasis to the scalene nodes were subsequently treated with extended field radiation therapy and were then eligible for a randomized trial of systemic chemotherapy. Only four patients were found to have micrometastases to the scalene fossa. This figure is appreciably lower than that reported in previous literature. While geographic failure continues to be a problem for this group of patients, routine use of left scalene fat pad biopsy before treatment is not recommended.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adipose Tissue / pathology*
  • Adult
  • Aged
  • Aorta, Abdominal
  • Biopsy, Needle
  • Carcinoma, Squamous Cell / drug therapy
  • Carcinoma, Squamous Cell / pathology*
  • Carcinoma, Squamous Cell / radiotherapy
  • Cisplatin / therapeutic use
  • Combined Modality Therapy
  • Female
  • Humans
  • Hydroxyurea / therapeutic use
  • Lymphatic Metastasis
  • Middle Aged
  • Muscles / pathology*
  • Neck Muscles / pathology*
  • Neoplasm Staging
  • Prospective Studies
  • Risk Factors
  • Uterine Cervical Neoplasms / drug therapy
  • Uterine Cervical Neoplasms / pathology*
  • Uterine Cervical Neoplasms / radiotherapy

Substances

  • Cisplatin
  • Hydroxyurea