Axillary reverse mapping (ARM): where to go

Breast Cancer. 2019 Jan;26(1):1-10. doi: 10.1007/s12282-018-0886-0. Epub 2018 Jun 30.

Abstract

In the past decades, breast surgeons have changed the clinical practice in the surgical treatment of breast cancer, by performing sentinel lymph node biopsy (SLNB) instead of performing axillary lymph node dissection (ALND) in axillary lymph node clinically negative breast cancer patients. ALND can also be avoided in SLN-positive patients who meet the Z-0011 criteria. However, the postoperative complications of SLNB and ALND, such as the secondary upper extremity lymphedema, are common and need effective solutions to prevent as soon as possible. The axillary reverse mapping (ARM) technique has been developed to map and preserve arm lymphatic drainage during ALND and/or SLNB, thereby minimizing arm lymphedema. However, the success of ARM in reducing lymphedema has not been exactly determined. If ARM can be confirmed to be both effective and oncologically safe in preventing lymphedema, this technique should be recommended in the management of breast cancer treatment.

Keywords: Axillary lymph node dissection; Axillary reverse mapping; Breast cancer; Lymphedema; Sentinel lymph node biopsy.

Publication types

  • Review

MeSH terms

  • Axilla
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Contrast Media / administration & dosage
  • Contrast Media / adverse effects
  • Female
  • Humans
  • Lymph Node Excision / adverse effects
  • Lymph Node Excision / methods
  • Lymph Nodes / diagnostic imaging
  • Lymph Nodes / pathology
  • Lymphatic Metastasis / diagnostic imaging*
  • Lymphatic Metastasis / pathology
  • Lymphatic Vessels / diagnostic imaging
  • Lymphatic Vessels / pathology
  • Lymphedema / etiology
  • Lymphedema / prevention & control*
  • Mastectomy / adverse effects
  • Mastectomy / methods
  • Medical Oncology / methods
  • Optical Imaging / adverse effects
  • Optical Imaging / methods*
  • Organ Sparing Treatments / adverse effects
  • Organ Sparing Treatments / methods
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control*
  • Sentinel Lymph Node Biopsy / adverse effects
  • Sentinel Lymph Node Biopsy / methods

Substances

  • Contrast Media