A Different Perspective on Breast Implant Surface Texturization and Anaplastic Large Cell Lymphoma (ALCL)

Aesthet Surg J. 2019 Jan 1;39(1):56-63. doi: 10.1093/asj/sjy091.

Abstract

Anaplastic large cell lymphoma (ALCL) is a rare form of lymphoma involving cells of the immune system. It is currently gaining interest because of an association between the development of ALCL and an increased risk in women who have had breast implant surgery. Although not confirmed, many theories exist as to the etiology of this association in women, and there is growing concern that ALCL is more prevalent in women with textured breast implants. In particular, the risk of developing ALCL appears to be related to increasing implant texturization or "surface roughness." This paper examines the current manner of defining and characterizing breast implant surface texture and challenges the appropriateness of applying this technology and linking it to ALCL. It is not a comprehensive review of the etiology of capsular contracture and ALCL, but it proposes an alternative perspective on surface texture measurements from that currently employed and its role in researching the etiology of ALCL. The authors hope that their article will provoke thought and reflection when considering the issues currently being highlighted with regard to texturing of breast implants.

MeSH terms

  • Breast Implantation / adverse effects*
  • Breast Implantation / instrumentation
  • Breast Implants / adverse effects*
  • Breast Neoplasms / epidemiology*
  • Breast Neoplasms / etiology
  • Female
  • Humans
  • Implant Capsular Contracture / epidemiology*
  • Implant Capsular Contracture / etiology
  • Lymphoma, Large-Cell, Anaplastic / epidemiology*
  • Lymphoma, Large-Cell, Anaplastic / etiology
  • Prevalence
  • Risk Assessment
  • Surface Properties