Abstract
Vitamin C was first suggested to have cancer-fighting properties in the 1930s and has been the subject of controversy ever since. Despite repeated reports of selective cancer cell toxicity induced by high-dose vitamin C treatment in vitro and in mouse models, the mechanism of action has remained elusive.
MeSH terms
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Animals
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Ascorbic Acid / therapeutic use*
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Colorectal Neoplasms / drug therapy*
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Colorectal Neoplasms / genetics*
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Female
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Humans
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Proto-Oncogene Proteins / genetics*
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Proto-Oncogene Proteins B-raf / genetics*
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ras Proteins / genetics*
Substances
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Proto-Oncogene Proteins
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Proto-Oncogene Proteins B-raf
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ras Proteins
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Ascorbic Acid