Technical prerequisites and imaging protocols for dynamic and dual energy myocardial perfusion imaging

Paola M Cannaò; U Joseph Schoepf; Giuseppe Muscogiuri; Julian L Wichmann; Stephen R Fuller; Francesco Secchi; Akos Varga-Szemes; Carlo N De Cecco

doi:10.1016/j.ejrad.2015.02.010

Technical prerequisites and imaging protocols for dynamic and dual energy myocardial perfusion imaging

Eur J Radiol. 2015 Dec;84(12):2401-10. doi: 10.1016/j.ejrad.2015.02.010. Epub 2015 Feb 21.

Authors

Paola M Cannaò¹, U Joseph Schoepf², Giuseppe Muscogiuri³, Julian L Wichmann⁴, Stephen R Fuller⁵, Francesco Secchi⁶, Akos Varga-Szemes⁵, Carlo N De Cecco⁷

Affiliations

¹ Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; Scuola di Specializzazione di Radiodiagnostica, Università degli Studi di Milano, Milan, Italy.
² Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC, United States. Electronic address: schoepf@musc.edu.
³ Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; Department of Medical-Surgical Sciences and Translational Medicine, University of Rome "Sapienza", Rome, Italy.
⁴ Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt, Germany.
⁵ Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States.
⁶ Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; Department of Radiology, IRCCS Policlinico San Donato, San Donato Milanese, Italy.
⁷ Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States; Department of Radiological Sciences, Oncology and Pathology, University of Rome "Sapienza" - Polo Pontino, Latina, Italy.

PMID: 25779223
DOI: 10.1016/j.ejrad.2015.02.010

Abstract

Coronary CT angiography (CCTA) is an established imaging technique used for the non-invasive morphological assessment of coronary artery disease. As in invasive coronary angiography, CCTA anatomical assessment of coronary stenosis does not adequately predict hemodynamic relevance. However, recent technical improvements provide the possibility of CT myocardial perfusion imaging (CTMPI). Two distinct CT techniques are currently available for myocardial perfusion assessment: static CT myocardial perfusion imaging (sCTMPI), with single- or dual-energy modality, and dynamic CT myocardial perfusion imaging (dCTMPI). The combination of CCTA morphological assessment and CTMPI functional evaluation holds promise for achieving a comprehensive assessment of coronary artery anatomy and myocardial perfusion using a single image modality.

Keywords: Coronary CT angiography; Coronary artery disease; Dual energy CT; Invasive coronary angiography; Myocardial perfusion imaging.

Publication types

Review

MeSH terms

Coronary Angiography / methods*
Coronary Artery Disease / diagnostic imaging*
Coronary Stenosis / diagnostic imaging
Humans
Male
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*