Abstract
A common observation in sickle cell disease is growth retardation, in particular, wasting. Wasting is associated with increased hospitalization and possibly poorer clinical outcomes. Therefore understanding the mechanism of wasting is crucial and reducing the degree of wasting by improving the nutritional status, holds the potential for modifying the course of the disease.
Copyright © 2012 Académie des sciences. Published by Elsevier SAS. All rights reserved.
MeSH terms
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Adult
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Anemia, Sickle Cell / complications*
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Anemia, Sickle Cell / metabolism
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Anemia, Sickle Cell / physiopathology
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Anorexia / etiology
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Anorexia / physiopathology
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Appetite Regulation / physiology
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Basal Metabolism
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Body Composition
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Child
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Energy Intake
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Energy Metabolism
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Female
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Hemolysis / physiology
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Humans
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Inflammation Mediators / physiology
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Male
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Malnutrition / etiology
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Malnutrition / prevention & control*
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Motor Activity
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Nutritional Status
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Wasting Syndrome / etiology*
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Wasting Syndrome / prevention & control
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Young Adult