Laparoscopic splenectomy for massive splenomegaly in benign hematological diseases

Surg Endosc. 2012 Nov;26(11):3186-9. doi: 10.1007/s00464-012-2314-4. Epub 2012 May 12.

Abstract

Background: Laparoscopic splenectomy has become the standard of care for benign hematological disease affecting the spleen; its role in massive splenomegaly remains controversial. In this study, we evaluated the outcome of laparoscopic splenectomies in terms of spleen size in a group of 83 patients of benign hematological diseases.

Methods: From July 2003 to December 2009, 83 patients underwent laparoscopic splenectomy for various benign hematological diseases. The data were recorded and analyzed in a retrospective manner. The patients were divided in to two groups according to the spleen weight; group I < 2,000 g (n = 54) and group II > 2,000 g (n = 29). Age, sex, hematological condition, operative time, estimated blood loss, conversion to open surgery, splenic weight, length of hospital stay, time to liquid diet, and morbidity were all recorded.

Results: Laparoscopic splenectomy was completed in 79 patients (95.2 %). Operative time (p = 0.01) and estimated blood loss (p = 0.001) was more in group II. The length of hospital stay (p = 0.05) and the postoperative morbidity (p = 0.001) also were significantly more in the second group. There was no mortality.

Conclusions: Laparoscopic splenectomy is possible and safe for massive splenomegaly in hematological disease (>2,000 g), but it needs longer operative time and hospital stay.

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Hematologic Diseases / complications
  • Humans
  • Laparoscopy*
  • Male
  • Organ Size
  • Retrospective Studies
  • Splenectomy / methods*
  • Splenomegaly / etiology
  • Splenomegaly / pathology*
  • Splenomegaly / surgery*
  • Young Adult