[A case of stage IVb cervical carcinoma in which survival was prolonged by two different chemotherapies and CCRT]

Gan To Kagaku Ryoho. 2012 Mar;39(3):451-5.
[Article in Japanese]

Abstract

Pulmonary metastasis from primary cervical carcinoma is rare, with an incidence of 4.16-7.7%. Chemotherapy is the most common treatment; however, the overall prognosis is poor. This case report describes a complete response to CCRT and TC therapy of cervical carcinoma metastatic to the lung. The patient, a 57-year-old woman, was initially diagnosed with FIGO clinical Stage IVb cervical carcinoma with lung metastasis, after presenting with vaginal bleeding. She had a 90 pack/year smoking history. She was initially treated with systemic chemotherapy(TC therapy: PTX, CBDCA 1 course)followed by concurrent chemoradiotherapy(CCRT)with weekly CDDP2 0mg/m2. She had a complete response of her pelvic disease as well as a decrease in the size of metastatic lesions. Following CCRT, she was scheduled to continue TC therapy, but was only able to complete two courses secondary to a myocardial infarction. A lung biopsy at that time showed no evidence of malignancy, and the patient has remained without any evidence of disease for the past six years.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Chemoradiotherapy*
  • Female
  • Humans
  • Lung Neoplasms / secondary
  • Lung Neoplasms / therapy
  • Middle Aged
  • Neoplasm Staging
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / therapy*