Rhabdomyosarcoma: review of the Children's Oncology Group (COG) Soft-Tissue Sarcoma Committee experience and rationale for current COG studies

Pediatr Blood Cancer. 2012 Jul 15;59(1):5-10. doi: 10.1002/pbc.24118. Epub 2012 Feb 29.

Abstract

The prognosis for children and adolescents with rhabdomyosarcoma (RMS) has improved with refinements in multi-modal therapy. Since 1972, the Intergroup Rhabdomyosarcoma Study Group (now the Children's Oncology Group Soft-Tissue Sarcoma Committee) has conducted serial studies for RMS. This review describes the IRSG and COG experience with RMS, presents the current risk stratification definitions, and provides rationale for the current generation of COG RMS studies.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Biomedical Research / organization & administration
  • Biomedical Research / standards
  • Biomedical Research / trends
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Rhabdomyosarcoma / therapy*
  • Risk Factors