Abstract
Objective:
Lung cancer remains the leading cause of cancer mortality in both men and women. Tobacco use causes the vast majority of lung cancer in women but does not explain all cases, because about one in five women who develop lung cancer have never smoked.
Conclusion:
Environmental exposures, genetic predisposition, hormonal factors, and viral infection may all play a role in lung cancer in women. A better understanding may provide an avenue to more effective screening, diagnosis, and therapy.
MeSH terms
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Adenocarcinoma / diagnostic imaging
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Adenocarcinoma / epidemiology
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Adenocarcinoma / genetics
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Adenocarcinoma / pathology
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Adenocarcinoma / secondary
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Adenocarcinoma, Bronchiolo-Alveolar / diagnostic imaging
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Adenocarcinoma, Bronchiolo-Alveolar / epidemiology
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Adult
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Causality
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Comorbidity
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Early Detection of Cancer / statistics & numerical data*
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Environmental Exposure / adverse effects
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Environmental Exposure / statistics & numerical data
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Environmental Pollutants / adverse effects
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Female
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Genetic Predisposition to Disease
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Humans
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Incidence
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Infections / epidemiology
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Lung Neoplasms / diagnostic imaging
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Lung Neoplasms / epidemiology*
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Lung Neoplasms / genetics
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Lung Neoplasms / pathology
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Male
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Mass Screening / statistics & numerical data
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Middle Aged
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Radiography
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Radon / adverse effects
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Risk Factors
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Sex Distribution
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Smoking / epidemiology
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Survival Rate
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Tobacco Smoke Pollution / adverse effects
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Tobacco Smoke Pollution / statistics & numerical data
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United States / epidemiology
Substances
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Environmental Pollutants
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Tobacco Smoke Pollution
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Radon