Slower uptake of HIV antiretroviral therapy among Aboriginal injection drug users

J Infect. 2006 Apr;52(4):233-6. doi: 10.1016/j.jinf.2005.07.008. Epub 2005 Sep 19.

Abstract

Objectives: We examined the time to antiretroviral therapy (ART) use among antiretroviral naïve HIV infected injection drug users participating in a prospective cohort study in Vancouver, Canada.

Methods: Time to the initiation of ART was evaluated using Kaplan-Meier methods and Cox proportional hazards regression. The cohort was stratified based on Aboriginal and non-Aboriginal (primarily Caucasian) ethnicity.

Results: Between May 1996 and May 2003, 312 HIV-infected individuals were enrolled into the cohort. At 24 months after enrollment, the rate of ART use was 29.2% among Aboriginal participants and was 53.7% among non-Aboriginal participants (log-rank P=0.023), and lower uptake of ART persisted in multivariate analyses (relative hazard = 0.37 [95% CI: 0.15-0.93]; P = 0.035).

Conclusions: These findings demonstrate lower uptake of HIV/AIDS care among Aboriginal injection drug users and demonstrate the need for interventions to improve access to HIV care among indigenous populations.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Retroviral Agents / therapeutic use*
  • British Columbia
  • Cohort Studies
  • Delivery of Health Care / statistics & numerical data*
  • Female
  • HIV Infections / complications
  • HIV Infections / drug therapy*
  • HIV Infections / ethnology
  • Humans
  • Indians, North American*
  • Male
  • Proportional Hazards Models
  • Prospective Studies
  • Substance Abuse, Intravenous / complications*
  • Time Factors

Substances

  • Anti-Retroviral Agents