Anti-Candida activity of Brazilian medicinal plants

J Ethnopharmacol. 2005 Feb 28;97(2):305-11. doi: 10.1016/j.jep.2004.11.016. Epub 2005 Jan 5.

Abstract

Essential oils and ethanolic extracts from the leaves and/or roots of 35 medicinal plants commonly used in Brazil were screened for anti-Candida albicans activity. The oils were obtained by water-distillation using a Clevenger-type system. Essential oils from 13 plants showed anti-Candida activity, including Aloysia triphylla, Anthemis nobilis, Cymbopogon martini, Cymbopogon winterianus, Cyperus articulatus, Cyperus rotundus, Lippia alba, Mentha arvensis, Mikania glomerata, Mentha piperita, Mentha sp., Stachys byzantina, and Solidago chilensis. The ethanol extract was not effective at any of the concentrations tested. Chemical analyses showed the presence of compounds with known antimicrobial activity, including 1,8-cineole, geranial, germacrene-D, limonene, linalool, and menthol.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / isolation & purification*
  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use
  • Brazil
  • Candida albicans / drug effects*
  • Ethnopharmacology*
  • Medicine, Traditional*
  • Microbial Sensitivity Tests
  • Oils, Volatile / isolation & purification*
  • Oils, Volatile / pharmacology
  • Plant Extracts / isolation & purification*
  • Plant Extracts / pharmacology
  • Plant Leaves
  • Plant Oils / isolation & purification*
  • Plant Oils / pharmacology
  • Plant Roots
  • Plants, Medicinal*

Substances

  • Antifungal Agents
  • Oils, Volatile
  • Plant Extracts
  • Plant Oils