Introduction: Inflammatory fibroid polyp of the large intestine is uncommon. To our knowledge, this condition has not been reported in a patient with neurofibromatosis.
Clinical picture: In this report, a 66-year-old woman with neurofibromatosis was found to have a large polyp in the caecum.
Treatment: Right hemicolectomy was performed because of the size of the polyp.
Outcome: Pathological examination showed that the polyp was an inflammatory fibroid polyp.
Conclusion: Clinicians should be aware that inflammatory fibroid polyps could be one of the many manifestations of neurofibromatosis in the gastrointestinal tract.