Abstract
Renal toxicity of contrast agents remains an up-to-date challenge. N'Acetyl cystein is an antioxyde agent which efficacy has been proved in various models of experimental renal ischemia and therefore proposed in the prevention of renal failure due to intravenous iodine contrast media. The Author of this review reports and comments these studies in order to better define indications of N'Acetyl cystein in this clinical context.
MeSH terms
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Acetylcysteine / pharmacology
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Acetylcysteine / therapeutic use*
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Acute Kidney Injury* / chemically induced
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Acute Kidney Injury* / prevention & control
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Animals
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Antioxidants / pharmacology
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Antioxidants / therapeutic use*
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Contrast Media / adverse effects*
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Disease Models, Animal
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Drug Evaluation, Preclinical
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Free Radical Scavengers / pharmacology
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Free Radical Scavengers / therapeutic use*
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Humans
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Iodine Radioisotopes / adverse effects*
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Risk Factors
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Treatment Outcome
Substances
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Antioxidants
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Contrast Media
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Free Radical Scavengers
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Iodine Radioisotopes
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Acetylcysteine