Clinical study of the Ginko biloba--Troxerutin-Heptaminol Hce in the treatment of acute hemorrhoidal attacks

J Med Assoc Thai. 2004 Feb;87(2):137-42.

Abstract

Objective: The aim of this study was to assess the clinical efficacy, compliance and safety of Ginko biloba--Troxerutin-Heptaminol Hce in the treatment of patients with acute hemorrhoidal attacks in Thailand.

Material and method: In a prospective clinical study on hospital outpatients, the authors studied the effect of Ginko biloba--Troxerutin-Heptaminol Hce for a week in adults (18-70 years old) with acute hemorrhoidal attacks.

Result: Twenty-two patients, with a mean age of 41.7 years were included in the study. The male to female ratio was 1 : 1.2. Most patients (77%) had grade 1 and 2 hemorrhoids with an average duration of attacks of 3 days. On intention to treat analysis, bleeding, pain, tenesmus and discharge were significantly improved. Treatment was well accepted and safe.

Conclusion: In the short-term, Ginko biloba--Troxerutin-Heptaminol Hce is effective, acceptable and safe in the treatment of patients with acute hemorrhoidal attacks.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Aged
  • Drug Therapy, Combination
  • Female
  • Follow-Up Studies
  • Ginkgo biloba*
  • Hemorrhoids / diagnosis
  • Hemorrhoids / drug therapy*
  • Heptaminol / therapeutic use*
  • Humans
  • Hydroxyethylrutoside / analogs & derivatives
  • Hydroxyethylrutoside / therapeutic use*
  • Male
  • Middle Aged
  • Pain Measurement
  • Phytotherapy / methods*
  • Prospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Hydroxyethylrutoside
  • Heptaminol
  • troxerutin