The PPARs: from orphan receptors to drug discovery

J Med Chem. 2000 Feb 24;43(4):527-50. doi: 10.1021/jm990554g.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Diabetes Mellitus / drug therapy
  • Diabetes Mellitus / metabolism
  • Drug Design*
  • Humans
  • Hyperlipidemias / drug therapy
  • Hyperlipidemias / metabolism
  • Hypertension / drug therapy
  • Hypertension / metabolism
  • Inflammation / drug therapy
  • Inflammation / metabolism
  • Ligands
  • Models, Molecular
  • Neoplasms / drug therapy
  • Neoplasms / metabolism
  • Nuclear Proteins / physiology*
  • Obesity / drug therapy
  • Obesity / metabolism
  • Receptors, Cytoplasmic and Nuclear / chemistry
  • Receptors, Cytoplasmic and Nuclear / drug effects*
  • Receptors, Cytoplasmic and Nuclear / metabolism
  • Receptors, Cytoplasmic and Nuclear / physiology*
  • Transcription Factors / chemistry
  • Transcription Factors / drug effects*
  • Transcription Factors / metabolism
  • Transcription Factors / physiology*

Substances

  • Ligands
  • Nuclear Proteins
  • Receptors, Cytoplasmic and Nuclear
  • Transcription Factors