ORIGINAL ARTICLEChronic Cough From the Patient's Perspective
Section snippets
PATIENTS AND METHODS
All consecutive patients referred to the Mayo Clinic Division of Pulmonary and Critical Care Medicine outpatient clinic with a patient-provided complaint of chronic cough between November 1, 2000, and February 28, 2001, were prospectively surveyed for cough-related complaints. Patients were asked to participate in the survey with the objective of improving our understanding of their perceptions and needs regarding their cough problem. The questionnaire was handed to patients as they entered the
RESULTS
A total of 146 consecutive patients with a chief complaint of chronic cough were asked to participate, and 146 completed the cough-related adverse event survey in the 12-week study period. There were no nonresponders. Afterexcluding 10 patients because the requisite duration of cough could not be confirmed in 9 and was less than 3 weeks in 1, 136 patients were included in the analysis. Table 1 presents the demographic and clinical data of the patients included in the study. There were no
DISCUSSION
In this prospective study, we characterized areas of QOL impairment in patients with chronic cough evaluated at a tertiary care referral center. One of our most interesting findings was that interference with lifestyle and leisure; frequent physician visits; feelings of frustration, irritability, or anger; and sleep disturbances were identified most commonly by patients as major cough-related problems, surpassing anxiety about an underlying illness by a wide margin. This finding is in contrast
CONCLUSIONS
This study shows that patients referred for evaluation for chronic cough to a tertiary care center present with a high frequency of somatic and psychological complaints. Irritability, anger, frequent physician visits and testing, sleep disturbances, and interference with lifestyle and leisure are the most prevalent cough-related symptoms in this patient population. Patients are often concerned that their cough is a symptom of a serious underlying illness, whereas physicians often view cough as
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Cited by (53)
The scourge of chronic cough
2024, PulmonologyStandardized Behavioral Treatment Improves Chronic Cough
2023, Journal of VoiceDemographic, clinical, and patient-reported outcome data from 2 global, phase 3 trials of chronic cough
2023, Annals of Allergy, Asthma and ImmunologyCitation Excerpt :Patients with CC experience a substantial physical and psychosocial burden. In a survey of 136 patients with CC in the United States, 66% reported experiencing exhaustion or poor concentration.6 When 210 women presenting for evaluation of CC at a US specialty clinic were asked specifically about the complication of stress urinary incontinence (SUI), 63% reported SUI associated with coughing episodes.7
Referrals, etiology, prevalence, symptoms, and treatments of chronic cough: A survey of allergy specialists
2022, Annals of Allergy, Asthma and ImmunologyCitation Excerpt :Chronic cough (CC) affects approximately 11% of the US1 adult population and is defined as a cough that persists longer than 8 weeks and remains unexplained after therapeutic trials are completed.2 CC has been associated with pain, urinary incontinence, sleep disturbance, depression, anxiety, social stigma (social distress or isolation and embarrassment), and life-threatening events (ruptured spleen, artery dissection).3,4 CC has a negative effect on health-related quality of life,5 with patients reporting an average of 8 adverse symptoms associated with their CC.6
The disease burden and quality of life of chronic cough patients in South Korea and Taiwan
2022, World Allergy Organization JournalCitation Excerpt :Furthermore, CC patients in both nations more frequently reported anxiety, depression, and insomnia than non-CC controls. Similar to our findings, previous studies also identified that the prevalence of insomnia or sleep disturbances was significantly associated with persistent cough and other respiratory symptoms.33–36 About 33% of patients with sleep-disordered breathing reportedly had chronic cough36 Disturbed sleep, anxiety and depression were also reported in more than half of the CC patients in a UK study.37