Chest
Selected ReportsAdamantinoma of the Tibia with Pulmonary Metastases and Hypercalcemia
Section snippets
Case Report
The patient was admitted to the hospital in 1959 when she was 13 years old with a pathologic tratture of the left tibia. Histologic material was not available for review. The diagnosis of adamantinoma was made in 1964, following curettage of a local recurrence.
In April 1987, she developed hemoptysis. A chest radiograph showed nodular densities in both lungs and a right-sided pleural effusion (Fig 1). Bronchoscopy revealed endobronchial lesions with histologic confirmation of adamantinoma in the
Discussion
This case history illustrates the typical clinical course of an adamantinoma of the tibia. Metastatic spread occurred to the lungs and the skeleton, the localizations most frequently cited in the literature.4 The patient ultimately died 24 years after the diagnosis of adamantinoma was made, illustrating the protracted evolution and the late occurrence of metastases.5 Curettage and local excision are inadequate treatment and often lead to local recurrence and metastatic disease. Although large
References (6)
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Adamantinoma of long bone: an analysis of nine new cases with emphasis on metastasizing lesions and fibrous dysplasia-like changes
Hum Pathol
(1977) - et al.
The treatment of adamantinoma of the tibia by wide resection and allograft bone transplantation
J Bone Joint Surg
(1987) - et al.
Adamantinoma of the appendicular skeletonupdated
Clin Orthop
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Cited by (21)
Malignant ameloblastoma: Concurrent presentation of primary and distant disease and review of the literature
2012, Journal of Oral and Maxillofacial SurgeryRadiologic-pathologic findings of primary osseous adamantinoma with unusual metastasis to the posterior cul-de-sac in pregnancy
2011, Clinical ImagingCitation Excerpt :Additionally, our patient had metastatic disease to the lungs, liver and retroperitoneum, which collectively have not been previously reported in a single patient to our knowledge. Metastatic foci have previously been reported to the ribs, lung, pleura, femur, humerus and spine [1–3]. Hazelbag et al. reported metastases to the lung and lymph nodes in 29% of 32 patients diagnosed with adamantinoma of the long bones with a clinical follow-up of 122 months [4].
Adamantinoma of the Tibia Mimicking a Benign Cystic Lesion: A Case Report
2010, Clinics in Podiatric Medicine and SurgeryCitation Excerpt :The tumor usually metastasizes to the lungs, the regional lymph nodes, or the bones.8,58 Rare pleuropulmonary manifestations, such as hemoptysis, pneumothorax,6,59 severe paraneoplastic, humorally mediated hypercalcemia, hypercalcemic coma, and pancreatitis have also been reported.58 In this article the imaging findings, diagnosis, and treatment of a patient with a distal tibial adamantinoma presenting as a cystic lesion is presented.
Adamantinoma: An updated review
2021, In VivoA case of progressive, metastatic adamantinoma in a pediatric patient
2021, Pediatric Blood and Cancer