StomachImpact of different sarcopenia stages on the postoperative outcomes after radical gastrectomy for gastric cancer
Section snippets
Patients
From August 2014 to December 2015, all patients who underwent radical gastrectomy for gastric cancer at the Gastrointestinal Surgical Department, The First Affiliated Hospital of Wenzhou Medical University, Whenzhou, China, were included in this study. The inclusion criteria included patients who (1) were ≥18 years old; (2) were American Society of Anesthesiologists (ASA) grade III; (3) planned to receive elective gastrectomy for gastric cancer with curative intent; (4) had preoperative
Results
From August 2014 to December 2015, a total of 470 patients met the inclusion criteria and took part in the study. Patient demographic and clinical characteristics are described in Table I.
Based on the diagnostic criteria, 97 (20.6%), 47 (10%), and 32 (6.8%) of patients were identified as having “presarcopenia,” “sarcopenia,” and “severe sarcopenia,” respectively, whereas 294 (62.6%) of patients were identified as “normal.” In the presarcopenia subgroup, 97 patients had low muscle mass and no
Discussion
The present study is the first to apply the EWGSOP sarcopenia classification in operative patients. We prospectively enrolled a large sample size to identify the patients with different stages of sarcopenia. The incidence of presarcopenia, sarcopenia, and severe sarcopenia was 20.6%, 10%, and 6.8%, respectively. Postoperative complications, duration of hospital stays, and hospital costs increased gradually with advancing stages of sarcopenia. Multivariate analysis demonstrated that severe
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Supported by the Shanghai Science and Technology Committee (16411954200), the foundation of the Health Department of Zhejiang province (2016139771), and the clinical nutriology of the medical supporting discipline of Zhejiang province.
All authors reported no biomedical financial interests or potential conflicts of interest.
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These authors contributed equally to this work.