Original articleWHO classification of meningiomas–A single institutional experience
Section snippets
Method
We conducted a retrospective study of all surgical biopsies diagnosed as meningiomas in our hospital facility for over twenty years. The study location, the University College Hospital, was the biggest hospital facility in the southwest region of Nigeria during the study period and regarded as the premier center for neurosurgery in the country.
Reports of all previously diagnosed meningiomas were retrieved and the tissue sections re-examined individually by two pathologists to confirm the
Results
During the study period, 756 patients with intracranial tumors were attended to in the hospital facility and 171 biopsies were diagnosed histologically as meningioma. Eight of the cases were excluded from the study for lack of adequate data, while 163 cases were included. The age range of the patients was from 7months to 78yrs, but most of the patients were adults. The mean age for all the patients was 45yrs ± 15.72 (Table 1), however, most of the patients had their ages within the fourth to the
Discussion
Previous studies done in colder climes have shown a higher occurrence of meningiomas in females as compared with males, and this is similar to what was seen in our data (Table 2). However, the male-female ratio of 1:1.4 seen in the index study suggests that the difference between the genders is narrower in blacks as compared to Caucasians in which the ratio usually is more than 1:2 [10], [14], [15], [16]. This finding is similarly buttressed by previous studies, which had shown similar gender
Limitations
The major limitation of this study is the fact that it is from a single hospital and the data may portray the patient referrals to the facility. It may not reflect the complete epidemiology of meningioma in the population. Another limitation of this study is the poor follow-up of diagnosed patients which prevented the recurrence of the tumour in the study population to be determined.
Conclusion
Although this study suggests a difference in the gender ratio of patients with meningioma in blacks compared with Caucasians, a larger, preferable population-based study is needed to provide reliable epidemiological data on the occurrence of meningiomas in blacks.
Human and animal rights
The authors declare that the work described has not involved experimentation on humans or animals.
Informed consent and patient details
The authors declare that this report does not contain any personal information that could lead to the identification of the patient(s) and/or volunteers.
Authors’ contributions
All authors attest that they meet the current International Committee of Medical Journal Editors (ICMJE) criteria for Authorship.
Disclosure of interest
The authors declare that they have no competing interest.
References (33)
- et al.
A retrospective analysis of meningioma in Central Texas
JEGH
(2016) - et al.
Descriptive epidemiology of 13,038 newly diagnosed and histologically confirmed meningiomas in France: 2006-2010
Neurochirurgie
(2018) - et al.
Incidence, mortality and outcome of meningiomas: A population-based study from Germany
Cancer Epidemiology
(2019) - et al.
Pediatric Meningiomas in Southwestern Nigeria: A Single-Institutional Experience
World Neurosurgery
(2019) - et al.
Histological classification and molecular genetics of meningiomas
The Lancet Neurology
(2006) Meningiomas
- et al.
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2012-2016
Neuro-Oncology
(2019) - et al.
Descriptive epidemiology of CNS tumors in France: results from the Gironde Registry for the period 2000-2007
Neuro-Oncology
(2011) - et al.
Epidemiological study of primary intracranial tumors: a regional survey in Kumamoto prefecture in southern Japan–20-year study
Int J Clin Oncol
(2011) - et al.
Histopathological pattern of intracranial neoplasms in a neurosurgical centre in Nigeria
Annals of Tropical Pathology
(2016)
Intracranial neoplasms in Ibadan, Nigeria
East African Medical Journal
Intracranial meningiomas managed at Memfys hospital for neurosurgery in Enugu, Nigeria
Journal of Neurosciences in Rural Practice
Epidemiology and etiology of intracranial meningiomas: a review
Journal of Neuro-Oncology
Pathology and Molecular Genetics of Meningioma: Recent Advances
Neurol Med Chir(Tokyo)
Meningioma
Pathological classification and molecular genetics of meningiomas
Journal of Neuro-Oncology
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