Collective review
Solid Pseudopapillary Tumors of the Pancreas: Review of 718 Patients Reported in English Literature

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Methods

Since 1933, when the first article in the field of the pancreatic papillary neoplasms was reported by Lichtenstein,5 until December 2003 we found 210 articles that described 718 well-documented cases of pancreatic SPTs in the English literature. Each article was carefully studied and a database was created with all patients’ characteristics. The database included age, gender, symptoms, localization, size of the tumor, metastasis or invasions of adjacent tissues, treatment, and followup. Every

Results

It was interesting to find that 167 of 210 articles (79.5%) originated from the US, Europe, and Japan. Respectively, 582 patients came from those three regions, representing 81.1% of the total number of patients. Table 1 presents those cases that fulfill the criteria that qualify them as well-documented.

Among 690 patients (96.10%), 64 were men and 626 were women (9.78:1). Mean age of the 710 patients (98.89%) with available age data was 21.97 years (ranging from 2 to 85 years). Figure 1 shows

History

Four articles played a decisive roll in the history of SPTs. Lichtenstein,5 Franz,7 Klöppel,18 and WHO.19 At necropsy, 5 years after her initial presentation, a papillary cystadenocarcinoma in the tail of the pancreas was found, which had metastasized to the peritoneum, omentum, and liver. In 1959, Franz7 described three patients, two women and one man, and recognized the special characteristics of the tumor. Between 1960 and 1980, several authors8, 9, 10, 11, 12, 13, 14, 15, 16, 17 wrote

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References (91)

  • P. Duff et al.

    Pregnancy complicated by solid-papillary epithelial tumor of the pancreas, pulmonary embolism, and pulmonary embolectomy

    Am J Obstet Gynecol

    (1985)
  • P.R. Dong et al.

    Solid and papillary neoplasm of the pancreasradiological-pathological study of five cases and review of the literature

    Clin Radiol

    (1996)
  • E.P. Nadler et al.

    The use of endoscopic ultrasound in the diagnosis of solid pseudopapillary tumors of the pancreas in children

    J Pediatr Surg

    (2002)
  • T. Kato et al.

    A case of solid pseudopapillary neoplasm of the pancreas and tumor doubling time

    Pancreatology

    (2002)
  • M. Horisawa et al.

    Frantz’s tumor (solid and cystic tumor of the pancreas) with liver metastasissuccessful treatment and long-term follow-up

    J Pediatr Surg

    (1995)
  • S. Kaufman et al.

    Papillary cystic neoplasms of the pancreasa curable pancreatic tumor

    World J Surg

    (1986)
  • K.Y. Lam et al.

    Pancreatic solid-cystic-papillary tumorclinicopathologic features in eight patients from Hong Kong and review of the literature

    World J Surg

    (1999)
  • D.S. Klimstra et al.

    Solid-pseudopapillary tumor of the pancreasa typically cystic carcinoma of low malignant potential

    Seminars Diagn Pathol

    (2000)
  • L. Lichtenstein

    Papillary cystadenocarcinoma of the pancreas

    Am J Cancer

    (1934)
  • J. Compagno et al.

    Solid and papillary epithelial neoplasm of the pancreas, probably of small duct origina clinicopathologic study of 52 cases

    Lab Invest

    (1979)
  • V.K. Frantz

    Tumors of the pancreas

    Atlas of tumor pathology, section VII, fascicles 27 and 28

    (1959)
  • A.B. Hamoudi et al.

    Papillary epithelial neoplasm of the pancreas in a childreport of a case and and electron microscopy

    Cancer

    (1970)
  • J.L. Bilton et al.

    Papillary cystadenocarcinoma of the pancreas

    Ohio State Med J

    (1974)
  • J.B. Taxy

    Adenocarcinoma of the pancreas in childhood. Report of a case and a review of the English language literature

    Cancer

    (1976)
  • B. Golematis et al.

    Papillary cystadenocarcinoma of the pancreas

    Am J Gastreonterol

    (1977)
  • P.J. Boor et al.

    Papillary-cystic neoplasm of the pancreas

    Am J Surg Pathol

    (1979)
  • A.L. Cubilla et al.

    Classification of pancreatic cancer (nonendocrine)

    Mayo Clin Proc

    (1979)
  • E. Benjamin et al.

    Adenocarcinoma of the pancreas of childhooda report of two cases

    Histopathology

    (1980)
  • P. Alm et al.

    A case of papillary-cystic epithelial neoplasm of the pancreas

    Acta Path Microbiol Scand

    (1981)
  • B.B. Cantrell et al.

    Acinar cell cystadenocarcinoma of human pancreas

    Cancer

    (1981)
  • G. Kloppel et al.

    Solid and cystic acinar cell tumour of the pancreas

    Virch Arch A Pathol Anat

    (1981)
  • G. Kloppel et al.
  • G. Pettinato et al.

    Papillary-cystic tumor of the pancreasa clinicopathologic study of 20 cases with cytologic, immunohistochemical, ultrastructural, and flow cytometric observations, and a review of the literature

    Am J Clin Pathol

    (1992)
  • L.P. Wunsch et al.

    Diagnosis and treatment of papillary cystic tumor of the pancreas in children. Case report

    Eur J Pediatr Surg

    (1997)
  • H. Takahashi et al.

    Solid cystic tumor of the pancreas in elderly menReport of a case

    Surg Today

    (1999)
  • H.E. Kennard

    Papillary cystadenocarcimona of the pancreas

    Surgery

    (1940)
  • L.W. Mason et al.

    Papillary cystadenocarcimona of the pancreas

    J Int Coll Surg

    (1954)
  • I. Forshall et al.

    An unusual islet-cell tumour of the pancreas

    Br J Surg

    (1952)
  • M.J. Radi et al.

    Functioning oncocytic islet-cell carcinoma

    Am J Surg Pathol

    (1985)

    Br J Surg

    (1952)
  • P.S. Boor et al.

    Papillary-cystic neoplasm of the pancreas

    Am J Surg Pathol

    (1979)

    Br J Surg

    (1952)
  • M.R. Lieber et al.

    Solid and papillary epithelial neoplasm of the pancreasan ultrastructural and immunocytochemical study of six cases

    Am J Surg Pathol

    (1987)

    Br J Surg

    (1952)
  • A.N. Kalloo et al.

    Solid and papillary epithelial neoplasm of the pancreasclinical findings of a rare tumor

    J Clin Gastroenterol

    (1990)

    Br J Surg

    (1952)
  • D.C. Schlosnagle et al.

    The papillary and solid neoplasm of the pancreasa report of two cases with electron microscopy, one containing neurosecretion granules

    Cancer

    (1981)
  • T.T. Kuo et al.

    Solid and papillary neoplasm of the pancreas. Report of three cases from Taiwan

    Cancer

    (1984)
  • H. Sanfey et al.

    Solid and papillary neoplasm of the pancreasa potentially curable surgical lesion

    Ann Surg

    (1983)
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    Competing Interests Declared: None.

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