Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Volume 1833, Issue 12, December 2013, Pages 3481-3498
ReviewAnoikis molecular pathways and its role in cancer progression☆
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Abbreviations
AMPK
AMP activated protein kinase
ECM
extracellular matrix
EGFR
epidermal growth factor receptor
EMT
epithelial–mesenchymal transition
ERK
extracellular signal-regulated kinase
FLIP
FLICE inhibitory protein
FAK
focal adhesion kinase
GSK-3
glycogen synthase kinase-3
HGF
hepatocyte growth factor
HIF
hypoxia-inducible factor
IL
interleukin
ILK
integrin-linked kinase
IKK
IκB kinase
MAPK
mitogen activated protein kinase
Mcl-1
myeloid cell leukemia sequence 1
MET
mesenchymal epithelial transition
MMP
metalloproteinase
NFκB
nuclear factor-κB
Nox
NADPH oxidase
OMM
outer mitochondrial membrane
PDGFR
platelet-derived growth factor receptor
PDK
pyruvate dehydrogenase kinase
PERK
protein kinase like endoplasmic reticulum kinase
PI3K
phosphoinositide-3-OH kinase
PIP3
phosphatidylinositol 3,4,5-triphosphate
PKB
protein kinase B
PK-M2
pyruvate kinase isoform-2
PPP
pentose phosphate pathway
PTEN
phosphatase and tensin homolog
ROS
reactive oxygen species
RTKs
receptor tyrosine kinases
SMA
α-smooth muscle actin
TNFR
tumor necrosis factor receptor
TrkB
tyrosine kinase receptor B
VEGFR
vascular endothelial growth factor receptor
Keywords
Anoikis
Cancer
MicroRNA
Metabolism
Reactive oxygen species
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This article is part of a Special Section entitled: Cell Death Pathways. Guest Editors: Frank Madeo and Slaven Stekovic.
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