Original articleGeneral thoracicRadioguided Detection of Lymph Node Metastasis in Non-Small Cell Lung Cancer
Section snippets
Patients and Methods
Our Institutional Review Board approved this pilot study in January 2004, and individual patient consent was obtained.
Results
We screened 12 patients (7 men) for the protocol. Two were ineligible owing to the diagnosis of a pulmonary granuloma in 1 patient and bulky mediastinal nodal disease in the other. The characteristics of the 10 eligible patients are summarized in Table 1. All of the patients had FDG-avid primary lung tumors on the preoperative PET scan, but 3 of 10 patients were staged as lymph node–negative by this preoperative scan (Table 2).
Mediastinoscopy revealed malignant ipsilateral lower paratracheal
Comment
It is estimated that there will be 174,470 new cases and 162,460 deaths from lung cancer in the United States in 2006 [1]. This accounts for more deaths than the estimates for prostate, breast, and colon cancer combined. Thus, the human and economic impact of lung cancer is enormous.
The staging of lung cancer plays a critical role in efforts to combat this disease, but progress in the ability to accurately identify all lymph node disease in patients has been limited. This is reflected in the
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