Original articleSclerosing Therapy as First Line Treatment for Low Flow Vascular Lesions of the Orbit
Section snippets
Material and methods
A prospective study of six patients with clinically or radiographically significant orbital lymphangiomas and one patient with cavernous hemangioma of the bone at the Jules Stein Eye Institute was conducted from January 2001 to July 2004. Patients were given 0.1-ml aliquots of sodium morrhuate 5% intralesionally or into the lymphatic cystic spaces to debulk the tumor in a nonsurgical manner. The main outcome measures for comparison purposes were lesion regression that was evident by clinical
Results
Seven patients (three male, four female; mean age, 33 years) were followed after sclerosing therapy for orbital lymphangioma (six patients) or intraosseous hemangioma (one patient); the mean duration of orbital tumor was 17 months. Six patients underwent previous debulking of lesion (one of these patients underwent four surgeries and required a skin graft); in one patient, no previous treatment was performed. Three of the six patients with anteriorly presenting orbital lymphangiomas had a
Discussion
Seven patients with low flow orbital vascular tumors were treated nonsurgically by intralesional injections of sodium morrhuate 5%. The outcome displayed an obvious improvement of these tumors.
Low flow vascular tumors can be difficult to treat and often bleed excessively at the time of surgery, with a high recurrence rate. Often these lesions are cosmetically unpleasing and demonstrate destruction of adjacent tissues. Surgical debulking of these lesions may result in marked disfigurement.
References (26)
- et al.
Orbital lymphangiomas
Ophthalmology
(1979) - et al.
An analysis of thirty cases of orbital lymphangiomapathophysiologic considerations and management recommendations
Ophthalmology
(1990) - et al.
Orbital-adnexal lymphangiomasa spectrum of hemodynamically isolated vascular hamartomas
Ophthalmology
(1986) Lymphangiomas of the ocular adnexaan analysis of sixty-two cases
Am J Ophthalmol
(1961)- et al.
Eyelid ecchymosis and proptosis in lymphangioma
Am J Ophthalmol
(1985) - et al.
Orbital cysts of childhoodclassification, clinical features, and management
Surv Ophthalmol
(2004) - et al.
Orbital venous anomalies
Ophthalmology
(1997) - et al.
Two cases of orbital lymphangioma associated with vascular abnormalities of the retina and iris
Ophthalmology
(2004) - et al.
Surgical management of orbital lymphangioma with the carbon dioxide laser
Am J Ophthalmol
(1986) - et al.
Sclerotherapy of oral and facial venous malformations with use of pingyangmycin and/or sodium morrhuate
Int J Oral Maxillofac Surg
(2004)
Sclerotherapy for venous malformations
J Pediatr Surg
Orbital lymphangiomaan analysis of 26 patients
Br J Ophthalmol
Orbital lymphangiomasclinical, radiologic, and pathologic characteristics
Radiology
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