Clinical studiesInterleukin-6, interferon-γ, interleukin-8, and granulocyte-macrophage colony stimulating factor levels in human amniotic fluid at term
References (31)
- et al.
Interleukin-8 production by the human cervix
Am. J. Obstet. Gynecol.
(1993) - et al.
Stimulation of collagen and glycosaminoglycan production in cultured adult dermal fibroblasts by recombinant human interleukin-6
J. Invest. Dermatol.
(1991) - et al.
Cytokine levels in amniotic fluid and inflammatory changes in the placenta from normal deliveries at term
Eur. J. Obstet. Gynecol. Reprod. Biol.
(1994) - et al.
Choriodecidual production of interleukin-8 and mechanism of parturition
Lancet
(1992) - et al.
Placental interleukin-6 production is enhanced in intrauterine infection but not in labor
Am. J. Obstet. Gynecol.
(1993) - et al.
Interleukin-6 stimulates prostaglandin production by human amnion and decidual cells
Eur. J. Pharmacol.
(1991) - et al.
Interleukin-6 in amniotic fluid obtained at forewater amniotomy compared with hindwater samples in women in spontaneous labour
Eur. J. Obstet. Gynecol. Reprod. Biol.
(1995) - et al.
Tumour necrosis factor, IL-1 and IL-6 in normal human pregnancy
Am. J. Obstet. Gynecol.
(1993) - et al.
IL-8 synthesis and the onset of labor
Obstet. Gynecol.
(1995) - et al.
A new view of prostaglandin E regulation of the immune response
Immunol. Today
(1991)
Neutrophil attractant/activating peptide-1/IL-8 in term and pre-term parturition
Am. J. Obstet. Gynecol.
The relationship between spontaneous rupture of membranes, labor, and microbial invasion of the amniotic cavity and amniotic fluid concentrations of prostaglandins and thromboxane B2 in term pregnancy
Am. J. Obstet. Gynecol.
Elevation of amniotic fluid IL-6, IL-8 and G-CSF in term and preterm parturition
Cytokine
Bidirectional cytokine interactions in the maternal fetal relationship: is successful pregnancy a TH2 phenomenon?
Immunol. Today
Immunohistochemical localization of interferons in human placental tissues in normal, ectopic and molar pregnancy
Am. J. Reprod. Immunol.
Cited by (53)
Imbalance between inflammatory and regulatory cord blood B cells following pre-term birth
2021, Journal of Reproductive ImmunologyCitation Excerpt :Interestingly, it has been shown that preterm infants overexpressed genes that are involved in the negative regulation of IFN-γ production (Olin et al., 2018). Moreover, IFN-γ was detected in AF of both labouring women and elective CS at term (Olah et al., 1996), suggesting that this cytokine is important in pregnancy and delivery but not at all indicative of inflammation related to premature delivery. IFN-γ increase as pregnancy progresses and is elevated around term and therefore decreased in AF samples of the PTB patients included in our study compared to TD.
Chorioamniotic membrane senescence: A signal for parturition?
2015, American Journal of Obstetrics and GynecologyEffects of the interleukin-6 (IL-6) polymorphism on toxic metal and trace element levels in placental tissues
2011, Science of the Total EnvironmentCitation Excerpt :Expression levels of inflammatory cytokines from trophoblasts and other cells in the normal placenta were previously reported (Kameda et al., 1990; Kauma et al., 1993). IL-6 levels in maternal serum (Arntzen et al., 1997), amniotic fluid (Olah et al., 1996), vaginal fluid (Imseis et al., 1997) and the placenta (Steinborn et al., 1996) were found to increase during the process of normal labor relative to the non-labor state. Previous work indicating a significant positive correlation between MT gene expression and IL-6 suggests that increased IL-6 expression is strictly related to an enhanced production of MTs (Giacconi et al., 2007).
Expression of sarcolectin in the human pituitary gland and amniotic fluid
2010, BiochimieCitation Excerpt :The titres are exceptionally high in the great majority of the specimens in correlation with high growth activity observed during these early periods of life. The presence of IFN in amniotic fluid was also detected but was very low as reported by others [13,14]. The low IFN titres could contribute to maintain differentiation.
Regulation of maternal serum and amniotic fluid cytokine profiles in the mouse: Possible roles in the onset of labour
2007, Journal of Reproductive ImmunologyCitation Excerpt :This concept is supported by the fact that advancing gestation in man features increased monocyte inflammatory responsiveness (Orsi et al., unpublished data). While parturition triggers remain ill-defined, they may involve a combination of fetal pulmonary and renal factors (Oláh et al., 1996; Condon et al., 2004) (Fig. 5). In particular, increased mouse fetal lung production of surfactant protein-A (SP-A) and phospholipids (e.g. arachidonic acid provision for prostaglandin synthesis) starts around day 17 of pregnancy and rises progressively until term, coincident with a fall in maternal progesterone.
Amniotic fluid cytokine profile in association with fetal hyperechogenic bowel
2006, European Journal of Obstetrics and Gynecology and Reproductive Biology
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Present address: Obstetrics and Gynaecology, Warwick Hospital, Lakin Road, Warwick CV34 5BW, UK.