Giant cell reparative granuloma outside the jaw bone: Diagnostic criteria and review of the literature with the first case described in the temporal bone
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Cited by (115)
A new case of Giant Cell ‘Reparative’ Granuloma of the temporal bone related to trauma
2017, Interdisciplinary Neurosurgery: Advanced Techniques and Case ManagementCitation Excerpt :Jaffe described Giant Cell Reparative Granuloma (GCRG) first in 1953 [1]. The first case of GCRG in the temporal bone was reported in 1974 by Hirschl and Katz [2]. Although GCRG is considered a benign lesion of bone, it is locally aggressive and requires surgical excision.
“Giant cell reparative tumor: An exceptional differential diagnosis for a lytic lesion of the temporal bone”
2016, NeurochirurgieCitation Excerpt :According to Saw et al. [2], there appears to be numerous overlapping features of giant cell tumour (GCT) and GCRG arising in the skull bones. Hirschl and Katz [5] (Table 1) defined five major histological criteria in order to distinguish between the two lesions, but there are also borderline cases, which show features of both. Both lesions appear more frequently in females however most patients with GCRG are less than 35 years old at the time of diagnosis while 20–33% of patients with GCT are over 50 years of age [12].
Pediatric aggressive giant cell granuloma of nasal cavity
2015, International Journal of Surgery Case ReportsCitation Excerpt :Non-surgical treatments include supplementary modalities such as corticosteroid intralesional injection, calcitonin, interferon alpha, and radiation. These procedures should be considered as secondary tools for lesions that cannot be completely resected because of higher possibility of additional surgery [9]. We learned a significant lesson about diagnosis & treatment through very interesting experience in the aggressive change after the first surgery.
Proliferative, reparative, and reactive benign bone lesions that may be confused diagnostically with true osseous neoplasms
2014, Seminars in Diagnostic PathologyCitation Excerpt :It is most often encountered in the mandible or, less commonly, the maxilla60–63 (Fig. 11). Cranial bones are only rarely affected.63,64 Multiple lesions in the mandible, particularly if they are symmetric and bilateral, may present the image of the heritable disease known as “cherubism.”65
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Assistant Professor, Department of Pathology and Experimental Pathology, New York Medical College. Associate Attending Pathologist, Flower and Fifth Avenue Hospitals, New York, New York.
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Assistant Professor, Department of Otolaryngology, New York Medical College. Assistant Attending Physician, Department of Surgery, Head and Neck Service, Memorial Hospital, New York, New York.