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Cited by (74)
Urinary Bladder, Ureter, and Urethra
2017, Boorman's Pathology of the Rat: Reference and AtlasJuvenile animal testing of hydroxypropyl-β-cyclodextrin in support of pediatric drug development
2015, Reproductive ToxicologySelection of appropriate tumour data sets for Benchmark Dose Modelling (BMD) and derivation of a Margin of Exposure (MoE) for substances that are genotoxic and carcinogenic: Considerations of biological relevance of tumour type, data quality and uncertainty assessment
2014, Food and Chemical ToxicologyCitation Excerpt :Chemically-induced bladder calculi or microcrystals in the rat or mouse bladder lumen lead to inflammation, hyperplasia and an increase in cellular proliferation and eventually to urothelial neoplasms. If doses of chemicals are administered below the amount necessary for calculus formation, no effects on the urothelium are produced (Clayson et al., 1995; Cohen, 1995, 1998). The rat, particularly the male rat, appears to be particularly susceptible to the formation of urinary precipitate (Cohen et al., 2000).
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2013, Haschek and Rousseaux's Handbook of Toxicologic Pathology, Third Edition: Volume 1-3Long-term treatment with l-isoleucine or l-leucine in AIN-93G diet has promoting effects on rat bladder carcinogenesis
2012, Food and Chemical Toxicology
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