Elsevier

Surgical Neurology

Volume 44, Issue 3, September 1995, Pages 208-223
Surgical Neurology

Prognostic factors in low-grade supratentorial astrocytomas: A uni-multivariate statistical analysis in 76 surgically treated adult patients

https://doi.org/10.1016/0090-3019(95)00184-0Get rights and content

Abstract

A retrospective uni-multivariate statistical analysis was performed on 32 prognostic factors to investigate their importance in predicting survival in a series of 76 adult patients with low-grade supratentorial astrocytomas treated over a 13-year period. The end point used for this study was the length of survival. The median survival time was 40 months. Overall actuarial survival at 2, 5, and 10 years was 69%, 38%, and 22%, respectively.

Radical resection of the neoformation, a higher preoperative Karnofsky performance status (KPS) score, and an age younger than 50 years are strongly correlated with survival; postoperative radiotherapy appears to be associated with increased survival only in patients under 50 years of age.

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