Peripheral odontogenic keratocyst

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Abstract

The gingival cyst of the adult exhibits an epithelial lining that is essentially the same as the lateral periodontal cyst. Although the gingival cyst of the adult exhibits some morphologic variability, its lining is generally considered to be nonkeratinized. Nonetheless, rare cases of gingival cyst of the adult that exhibit a keratinized epithelial lining have been reported in the literature. There is now a growing tendency to consider this variant as a separate entity. This article describes six cases of gingival cysts that exhibit the histologic features of the odontogenic keratocyst. Evidence from this series suggests that the biologic behavior of this subset of gingival cysts is different from that of the generic gingival cyst of the adult and that the termperipheral odontogenic keratocyst more accurately describes this entity.

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Cited by (30)

  • The extra-osseous odontogenic keratocyst: An anachronism?

    2022, Journal of Stomatology, Oral and Maxillofacial Surgery
    Citation Excerpt :

    A total of 37 reports on EOKC's occurring in the maxillofacial area were found in the literature. Twenty were located in the soft tissues of the mouth (Table 1) [4–19], whilst seventeen presented as gingiva cysts (Table 2) [20–28]. An additional two cases of gingiva cysts, ocurring in patients suffering from the nevoid basal cell carcinoma syndrome (NBCCS), were reported by Stoelinga et al. [29] and Sakamoto et al. [30].

  • Peripheral odontogenic keratocyst associated with nevoid basal cell carcinoma syndrome: A case report

    2014, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
    Citation Excerpt :

    Collectively, we made the final diagnosis of POKC, which was supported by immunohistochemical analysis and gene mutational analysis. Controversy exists over whether POKC is a locally destructive lesion with a high recurrence rate like KCOT or is an indolent lesion like gingival cyst of the adult.4,8 Ide et al.8 stated that POKC and KCOT are not extraosseous and intraosseous variants of the same entity.

  • Peculiar case of orthokeratinised odontogenic cyst: A peripheral counterpart of the intraosseous entity?

    2012, British Journal of Oral and Maxillofacial Surgery
    Citation Excerpt :

    It has therefore been described as the extraosseous counterpart of the KCOT.5,7–10 We know of only one report of a peripheral odontogenic keratocyst that had orthokeratinised epithelium.8 We present an OOC in a 49-year-old patient that involved the mandibular retromolar region and may have been a peripheral counterpart of the intraosseous OOC.

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