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Biopsy-proven brain metastases from prostate cancer: a series of four cases with review of the literature

  • Urology - Original Paper
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Abstract

Aims

Prostate cancer is very common and is the second most common cause of cancer death in males in Australia; however, brain metastases are exceedingly rare.

Materials and methods

We review four cases of biopsy-proven brain metastases from prostate cancer and review the relevant literature.

Results

Three of four patients had acinar adenocarcinoma of prostate with one patient having ductal adenocarcinoma variant on histopathology. Three patients had the brain as the only site of metastatic disease. All patients underwent surgery, and three of four patients underwent adjuvant palliative radiotherapy to the brain.

Conclusion

Brain metastases from prostate cancer are rare, but brain metastases without other sites of metastatic disease are exceedingly rare and may be more common with ductal adenocarcinoma variant.

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Conflict of interest

The authors wish to advise there is no conflict of interest to be reported.

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Correspondence to G. Hruby.

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Gzell, C.E., Kench, J.G., Stockler, M.R. et al. Biopsy-proven brain metastases from prostate cancer: a series of four cases with review of the literature. Int Urol Nephrol 45, 735–742 (2013). https://doi.org/10.1007/s11255-013-0462-7

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  • DOI: https://doi.org/10.1007/s11255-013-0462-7

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