Abstract
Purpose
To evaluate the technical feasibility and efficacy of percutaneous cryoablation for the treatment of osteoid osteoma (OO) in adults.
Methods and materials
21 patients (12 male and nine female; mean age, 29.9 years) who underwent CT-guided percutaneous cryoablation for the treatment of OO were retrospectively evaluated. Procedures were carried out under local anaesthesia and conscious sedation in 13 patients, and under general anaesthesia in eight patients. Then, the ablation zone was evaluated with post-procedure magnetic resonance imaging at 6 weeks. Clinical outcome was assessed using a visual analogue scale (VAS) to evaluate severity of pain before procedure, as well as at primary (6 weeks) and secondary follow-up (6-40 months).
Results
All procedures were technically successful. Median VAS scores were: 8 (range, 5-10) before procedure and after procedure, respectively, 0 (range, 0-2; p < .0001) and 0 (range, 0-7; p < .0001) at primary and secondary follow-up. There were three minor complications (14.3%) and no major complication. A single patient reported symptom recurrence (4.8%) at secondary follow-up and successfully underwent a second cryoablation procedure.
Conclusion
CT-guided percutaneous cryoablation is safe and effective in the treatment of OO in adults, and can be accomplished without general anaesthesia in selected cases.
Key Points
• CT-guided percutaneous cryoablation of osteoid osteoma is safe and effective
• Cryoablation allows precise visual control of the aggregated iceball during procedure
• Percutaneous cryoablation can be accomplished without general anaesthesia in selected cases
• Another advantage of cryoablation is reduction of immediate postprocedural pain
• Post-procedure MRI is helpful in the evaluation of technical success
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The scientific guarantor of this publication is Pr. Thomas Le Corroller.
Conflict of interest
The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.
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The authors state that this work has not received any funding.
Statistics and biometry
Dr. Vanessa Pauly kindly provided statistical advice for this manuscript.
No complex statistical methods were necessary for this paper.
Informed consent
Written informed consent was waived by the Institutional Review Board.
Ethical approval
Institutional Review Board approval was not required because thermal ablation already is the standard of care in our institution.
Methodology
• retrospective
• observational
• performed at one institution
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Santiago, E., Pauly, V., Brun, G. et al. Percutaneous cryoablation for the treatment of osteoid osteoma in the adult population. Eur Radiol 28, 2336–2344 (2018). https://doi.org/10.1007/s00330-017-5164-6
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DOI: https://doi.org/10.1007/s00330-017-5164-6