Abstract
We report the ultrasound, computed tomographic, and magnetic resonance imaging findings in a case of extramedullary hematopoiesis presenting as a focal splenic mass in a patient with myelodysplastic syndrome. Ultrasound demonstrated a well-circumscribed hyperechoic mass, whereas computed tomography showed a heterogeneous mass better visualized after administration of intravenous contrast. On magnetic resonance imaging, the lesion was hypointense to the spleen on T1-weighted images, with increased signal on T2-weighted images, and demonstrated enhancement after intravenous contrast administration. Extramedullary hematopoiesis should be considered in the differential diagnosis for a splenic mass in any patient with a hematologic disorder.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
A Aytac C Akyar C Atasoy S Erekul (1999) ArticleTitleFocal intrahepatic extramedullary hematopoiesis: color Doppler US and CT findings Abdom Imaging 24 366–368 Occurrence Handle10.1007/s002619900515 Occurrence Handle1:STN:280:DyaK1MzitFKmsg%3D%3D Occurrence Handle10390558
T Gabata M Kadoya A Mori et al. (2000) ArticleTitleMR imaging of focal splenic extramedullary hematopoiesis in polycythemia vera: case report Abdom Imaging 25 514–516 Occurrence Handle10.1007/s002610000045 Occurrence Handle1:STN:280:DC%2BD3cvpt12gtw%3D%3D Occurrence Handle10931988
M Navarro C Crespo L Perez et al. (2000) ArticleTitleMassive intrahepatic extramedullary hematopoiesis in myelofibrosis Abdom Imaging 25 184–186 Occurrence Handle10.1007/s002619910041 Occurrence Handle1:STN:280:DC%2BD3c7ktFWhsA%3D%3D Occurrence Handle10675463
B Mesurolle E Sayag P Meingan et al. (1996) ArticleTitleRetroperitoneal extramedullary hematopoiesis: sonographic, CT, and MR imaging appearance AJR 167 1139–1140 Occurrence Handle1:STN:280:ByiD28jotlw%3D Occurrence Handle8911166
D Warshauer M Schiebler (1991) ArticleTitleIntrahepatic extramedullary hematopoiesis: MR, CT, and sonographic appearance J Comput Assist Tomogr 15 683–685 Occurrence Handle1:STN:280:By6B1cnltFE%3D Occurrence Handle2061490
Braunwald E, Fauci AS, Kasper DL, et al, eds. Harrison’s principles of internal medicine, 15th ed. New York: McGraw-Hill, 2001:698–700
D Katz (1999) ArticleTitleSplenic extramedullary hematopoiesis: large focal lesion in a patient with thalassemia AJR 173 1715–1716 Occurrence Handle1:STN:280:DC%2BD3c%2FkvFGhtA%3D%3D Occurrence Handle10584831
L Gellett M Williams G Vivian (2001) ArticleTitleFocal intrasplenic extramedullary hematopoiesis mimicking lymphoma Clin Nucl Med 26 145–175 Occurrence Handle10.1097/00003072-200102000-00011 Occurrence Handle1:STN:280:DC%2BD3M7pt1Snsw%3D%3D Occurrence Handle11201473
T Yokoyama K Saigo N Maeda et al. (2000) ArticleTitleTumor-like splenic extramedullary hematopoiesis in a patient with myelofibrosis Intern Med 39 416–418 Occurrence Handle1:STN:280:DC%2BD3cvjtlSnuw%3D%3D Occurrence Handle10830186
MJ Bradley C Metrewli (1990) ArticleTitleUltrasound appearances of extramedullary haematopoiesis in the liver and spleen Br J Radiol 63 816–818 Occurrence Handle1:STN:280:By6D2Mrit1U%3D Occurrence Handle2242486
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Singer, A., Maldjian, P. & Simmons, M. Extramedullary hematopoiesis presenting as a focal splenic mass: a case report. Abdom Imaging 29, 710–712 (2004). https://doi.org/10.1007/s00261-003-0164-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00261-003-0164-1