Abstract
A case of cherubism in 6-year-old boy is reported. He presented with bilateral symmetrical enlargement of the jaw in addition to medially dislocated premature teeth, narrow V-shaped palatal vault, and mild upward turning of the eyes. Radiographs showed multiloculated osteolysis in both the mandible and maxilla. Histology revealed a non-neoplastic fibrous lesion, rich in multinucleated giant cells, consistent with giant-cell reparative granuloma. Since the original description of cherubism, various histologic interpretations have been proposed, particularly that of fibrous dysplasia. However, it should be emphasized that cherubism is a disease histologically indistinguishable from giant-cell reparative granuloma.
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Received: 30 November 1998 Revision requested: 5 January 1999 Revision received: 16 February 1999 Accepted: 19 February 1999
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Yamaguchi, T., Dorfman, H. & Eisig, S. Cherubism: clinicopathologic features. Skeletal Radiol 28, 350–353 (1999). https://doi.org/10.1007/s002560050530
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DOI: https://doi.org/10.1007/s002560050530