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Adamantinoma in childhood: report of six cases and review of the literature

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Abstract

Background

Adamantinoma is a rare slow-growing malignant bone tumour.

Objective

To describe the imaging appearances of six childhood cases and review the published literature.

Materials and methods

The database of the Working Group on Paediatric Oncology, Academic Medical Centre/Emma Children’s Hospital Amsterdam, was searched for cases of adamantinoma. Additionally a literature study was performed to identify cases of adamantinoma in childhood.

Results

We identified six local cases of adamantinoma of the long bones, two boys (age 3 and 8 years) and four girls (mean age 8.8 years, range 3.0–14.0 years). The location of the tumour was the tibia in five and the tibia and fibula in one patient. In two patients initially a different diagnosis was made, which led to a delay in appropriate treatment. None of the children showed pulmonary metastases and all underwent total gross resection. On follow-up (mean 6.1 years, range 1.6–12.0 years) all children remained disease-free. Besides a discussion of our six patients, imaging features, histopathology, surgical approach and a literature review of childhood adamantinomas is presented.

Conclusion

Although the incidence of adamantinoma is low, it is important to recognize this rare bone tumour, since in the early stages of the disease adequate treatment will result in an excellent prognosis.

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Authors and Affiliations

  1. Department of Radiology, Academic Medical Center Amsterdam, Meibergdreef 9, Amsterdam, Zuid-Oost 1105 AZ, The Netherlands

    Rick Van Rijn & Mario Maas

  2. Department of Pathology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands

    Johannes Bras

  3. Department of Orthopaedic Surgery, Academic Medical Center Amsterdam, Amsterdam, The Netherlands

    Gerard Schaap

  4. Department of Paediatric Oncology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands

    Henk van den Berg

Authors
  1. Rick Van Rijn
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  2. Johannes Bras
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  3. Gerard Schaap
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  4. Henk van den Berg
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  5. Mario Maas
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Correspondence to Rick Van Rijn.

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Van Rijn, R., Bras, J., Schaap, G. et al. Adamantinoma in childhood: report of six cases and review of the literature. Pediatr Radiol 36, 1068–1074 (2006). https://doi.org/10.1007/s00247-006-0272-5

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  • DOI: https://doi.org/10.1007/s00247-006-0272-5

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