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Quality of Life After Surgery for Rectal Cancer

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Book cover Early Gastrointestinal Cancers II: Rectal Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 203))

Abstract

Patients’ health-related quality of life (HRQoL) is now considered a relevant clinical outcome. This study systematically reviewed articles published in the last 5 years, focusing on the impact of rectal cancer treatment on patients’ HRQoL. Of the 477 articles retrieved, 56 met the inclusion criteria. The most frequently reported comparisons were between surgical procedures (21 articles), especially between sphincter-preserving and non-sphincter preserving surgery or between stoma and stoma-free patients (13 articles), and between multimodality therapies (11 articles). Additionally, twelve articles compared patients’ and healthy controls’ HRQoL as primary or secondary aim. The majority of the studies were observational (84 %), controlled (66 %), cross-sectional (54 %), prospective (100 %), with a sample of more than 100 patients (59 %), and with more than 60 % of patients treated with neoadjuvant therapy (50 %). The most frequently used instruments were the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (QLQ-C30), its colorectal cancer specific module QLQ-CR38, and the Medical Outcomes Study Short-Form 36 items questionnaire. Findings from the included articles are summarised and commented, with a special focus on the comparison between surgical treatments, between irradiated and not-irradiated patients, and between patients and the general population.

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References

  • Aaronson NK, Ahmedzai S, Bergam B, Bullinger M, Cull A, Duez NJ et al (1993) European Organisation for research and treatment of cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85(5):365–376

    Article  CAS  PubMed  Google Scholar 

  • Allaix ME, Rebecchi F, Giaccone C, Mistrangelo M, Morino M (2011) Long-term functional results and quality of life after transanal endoscopic microsurgery. Br J Surg 98(11):1635–1643. doi:10.1002/bjs.7584

    Article  CAS  PubMed  Google Scholar 

  • Andersson J, Angenete E, Gellerstedt M, Angerås U, Jess P, Rosenberg J et al (2013) Health-related quality of life after laparoscopic and open surgery for rectal cancer in a randomized trial. Br J Surg 100(7):941–949. doi:10.1002/bjs.9144

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Ashburn JH, Stocchi L, Kiran RP, Dietz DW, Remzi FH (2013) Consequences of anastomotic leak after restorative proctectomy for cancer: effect on long-term function and quality of life. Dis Colon Rectum 56(3):275–280. doi:10.1097/DCR.0b013e318277e8a5

    Article  PubMed  Google Scholar 

  • Austin KK, Young JM, Solomon MJ (2010) Quality of life of survivors after pelvic exenteration for rectal cancer. Dis Colon Rectum 53(8):1121–1126. doi:10.1007/DCR.0b013e3181e10c46

    Article  PubMed  Google Scholar 

  • Barisic G, Markovic V, Popovic M, Dimitrijevic I, Gavrilovic P, Krivokapic Z (2011) Function after intersphincteric resection for low rectal cancer and its influence on quality of life. Colorectal Dis 13(6):638–643. doi:10.1111/j.1463-1318.2010.02244.x

    Article  CAS  PubMed  Google Scholar 

  • Baxter NN, Novotny PJ, Jacobson T, Maidl LJ, Sloan J, Young-Fadok TM (2006) A stoma quality of life scale. Dis Colon Rectum 49:205–212. doi:10.1007/s10350-005-0275-6

    Article  PubMed  Google Scholar 

  • Bloemen JG, Visschers RG, Truin W, Beets GL, Konsten JL (2009) Long-term quality of life in patients with rectal cancer: association with severe postoperative complications and presence of a stoma. Dis Colon Rectum 52(7):1251–1258. doi:10.1007/DCR.0b013e3181a74322

    Article  PubMed  Google Scholar 

  • Bossema ER, Seuntiëns MW, Marijnen CA, Baas-Thijssen MC, van de Velde CJ, Stiggelbout AM (2011) The relation between illness cognitions and quality of life in people with and without a stoma following rectal cancer treatment. Psychooncology 20(4):428–434. doi:10.1002/pon.1758

    Article  PubMed  Google Scholar 

  • Bosset JF, Collette L, Calais G, Mineur L, Maingon P, Radosevic-Jelic L et al (2006) Chemotherapy with preoperative radiotherapy in rectal cancer. N Engl J Med 355:114–123. doi:10.1056/NEJMoa060829

    Article  Google Scholar 

  • Brændengen M, Tveit KM, Berglund Å, Birkemeyer E, Frykholm G, Påhlman L et al (2008) Randomized phase III study comparing preoperative radiotherapy with chemoradiotherapy in nonresectables rectal cancer. J Clin Oncol 26:3687–3694. doi:10.1200/JCO.2007.15.3858

    Article  PubMed  Google Scholar 

  • Braendengen M, Tveit KM, Hjermstad MJ, Johansson H, Berglund Å, Brandberg Y et al (2012) Health-related quality of life (HRQoL) after multimodal treatment for primarily non-resectable rectal cancer. Long-term results from a phase III study. Eur J Cancer 48(6):813–819. doi:10.1016/j.ejca.2011.06.035

    Article  PubMed  Google Scholar 

  • Bruheim K, Guren MG, Skovlund E, Hjermstad MJ, Dahl O, Frykholm G et al (2010) Late side effects and quality of life after radiotherapy for rectal cancer. Int J Radiat Oncol Biol Phys 76(4):1005–1011. doi:10.1016/j.ijrobp.2009.03.010

    Article  PubMed  Google Scholar 

  • Brundage M, Bass B, Davidson J, Queenan J, Bezjak A, Ringash J et al (2011) Patterns of reporting health-related quality of life outcomes in randomized clinical trials: implications for clinicians and quality of life researchers. Qual Life Res 20(5):653–664. doi:10.1007/s11136-010-9793-3

    Article  PubMed  Google Scholar 

  • Brundage M, Blazeby J, Revicki D, Bass B, de Vet H, Duffy H et al (2013) Patient-reported outcomes in randomized clinical trials: development of ISOQOL reporting standards. Qual Life Res 22(6):1161–1175. doi:10.1007/s11136-012-0252-1

    Article  PubMed Central  PubMed  Google Scholar 

  • Campos-Lobato LF, Alves-Ferreira PC, Lavery IC, Kiran RP (2011) Abdominoperineal resection does not decrease quality of life in patients with low rectal cancer. Clinics (Sao Paulo) 66(6):1035–1040

    Article  Google Scholar 

  • Canda AE, Terzi C, Gorken IB, Oztop I, Sokmen S, Fuzun M (2010) Effects of preoperative chemoradiotherapy on anal sphincter functions and quality of life in rectal cancer patients. Int J Colorectal Dis 25(2):197–204. doi:10.1007/s00384-009-0807-y

    PubMed  Google Scholar 

  • Caravati-Jouvenceaux A, Launoy G, Klein D, Henry-Amar M, Abeilard E, Danzon A et al (2011) Health-related quality of life among long-term survivors of colorectal cancer: a population-based study. Oncologist 16(11):1626–1636. doi:10.1634/theoncologist.2011-0036

    Article  PubMed Central  PubMed  Google Scholar 

  • Carlsson E, Berndtsson I, Hallén AM, Lindholm E, Persson E (2010) Concerns and quality of life before surgery and during the recovery period in patients with rectal cancer and an ostomy. J Wound Ostomy Continence Nurs 37(6):654–661. doi:10.1097/WON.0b013e3181f90f0c

  • Celasin H, Karakoyun R, Yılmaz S, Elhan AH, Erkek B, Kuzu MA (2011) Quality of life measures in Islamic rectal carcinoma patients receiving counselling. Colorectal Dis 13(7):e170–e175. doi:10.1111/j.1463-1318.2011.02649.x

    Article  CAS  PubMed  Google Scholar 

  • City of Hope/Beckman Research Institute Pain Resource Center Research Instruments. http://prc.coh.org/pdf/Quality%20of%20Life%20Ostomy.pdf

  • Cornish JA, Tilney HS, Heriot AG, Lavery IC, Fazio VW (2007) Tekkis PP. A meta-analysis of quality of life for abdominoperineal excision of rectum versus anterior resection for rectal cancer. Ann Surg Oncol 14(7):2056–2068. doi:10.1245/s10434-007-9402-z

    Article  PubMed  Google Scholar 

  • Detsky AS, Naglie IG (1990) A clinician’s guide to cost-effectiveness analysis. Ann Intern Med 113(2):147–154

    Article  CAS  PubMed  Google Scholar 

  • Doeksen A, Bakx R, Vincent A, van Tets WF, Sprangers MA, Gerhards MF et al (2012) J-pouch vs side-to-end coloanal anastomosis after preoperative radiotherapy and total mesorectal excision for rectal cancer: a multicentre randomized trial. Colorectal Dis 14(6):705–713. doi:10.1111/j.1463-1318.2011.02725.x

    Article  CAS  PubMed  Google Scholar 

  • Dumont F, Ayadi M, Goéré D, Honoré C, Elias D (2013) Comparison of fecal continence and quality of life between intersphincteric resection and abdominoperineal resection plus perineal colostomy for ultra-low rectal cancer. J Surg Oncol 108(4):225–229. doi:10.1002/jso.23379

    Article  CAS  PubMed  Google Scholar 

  • Dunn J, Lynch B, Aitken J, Leggett B, Pakenham K, Newman B (2003) Quality of life and colorectal cancer: a review. Aust N Z J Public Health 27(1):41–53

    Article  PubMed  Google Scholar 

  • Dupuy HJ (1984) The psychological general well being (PGWB) index. In: Wenger NK, Mattson ME, Furberg CD, Elinson J (eds) Assessment of quality of life in clinical trials of cardiovascular therapies. Le Jacq Publishing Inc, New York, pp 170–183

    Google Scholar 

  • Emmertsen KJ, Laurberg S (2013) Rectal cancer function study group. Impact of bowel dysfunction on quality of life after sphincter-preserving resection for rectal cancer. Br J Surg 100(10):1377–1387. doi:10.1002/bjs.9223

    Article  CAS  PubMed  Google Scholar 

  • Eypasch E, Williams JI, Wood-Dauphinee S, Ure BM, Schmulling C, Neugebauer E et al (1995) Gastrointestinal quality of life index: development, validation and application of a new instrument. Br J Surg 82:216–222. doi:10.1002/bjs.1800820229

    Article  CAS  PubMed  Google Scholar 

  • Fazio VW, O’Riordain MG, Lavery IC, Church JM, Lau P, Strong SA et al (1999) Long-term functional outcome and quality of life after stapled restorative proctocolectomy. Ann Surg 230:575–584. doi:10.1097/00000658-199910000-00013

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Fazio VW, Zutshi M, Remzi FH, Parc Y, Ruppert R, Fürst A et al (2007) A randomized multicentre trial to compare long-term functional outcome, quality of life, and complications of surgical procedures for low rectal cancers. Ann Surg 246:4818. doi:10.1097/SLA.0b013e3181485617

    Article  Google Scholar 

  • Fischer A, Tarantino I, Warschkow R, Lange J, Zerz A, Hetzer FH (2010) Is sphincter preservation reasonable in all patients with rectal cancer? Int J Colorectal Dis 25(4):425–432. doi:10.1007/s00384-010-0876-y

    PubMed  Google Scholar 

  • Gavaruzzi T, Giandomenico F, Pucciarelli S (2013) Quality of Life and Function After Chemoradiation for Rectal Cancer: a systematic review of recent publications. Curr Colorectal Cancer Rep. 9(2):157–167

    Article  Google Scholar 

  • Gavaruzzi T, Lotto L, Giandomenico F, Perin A, Pucciarelli S (2014) Patient reported outcomes after neoadjuvant therapy for rectal cancer: a systematic review. Expert Rev Anticancer Ther. doi: 10.1586/14737140.2014.911090

  • Guckenberger M, Saur G, Wehner D, Thalheimer A, Kim M, Germer CT et al (2013) Long-term quality-of-life after neoadjuvant short-course radiotherapy and long-course radiochemotherapy for locally advanced rectal cancer. Radiother Oncol 108(2):326–330. doi:10.1016/j.radonc.2013.08.022

    Article  PubMed  Google Scholar 

  • Gullà N, Trastulli S, Boselli C, Cirocchi R, Cavaliere D, Verdecchia GM et al (2011) Ghost ileostomy after anterior resection for rectal cancer: a preliminary experience. Langenbecks Arch Surg 396(7):997–1007. doi:10.1007/s00423-011-0793-8

    Article  PubMed  Google Scholar 

  • Guyatt GH, Feeny DH, Patrick DL (1993) Measuring health-related quality of life. Ann Intern Med 118(8):622–629

    Article  CAS  PubMed  Google Scholar 

  • Hays RD, Sherbourne CD, Mazel RM (1993) The RAND 36 - item health survey 1.0. Health economics 2(3):217–227. doi: 10.1002/hec.4730020305

  • Hennies S, Wolff HA, Jung K, Rave-Fränk M, Gaedcke J, Ghadimi M et al (2012) Testicular radiation dose after multimodal curative therapy for locally advanced rectal cancer. Influence on hormone levels, quality of life, and sexual functioning. Strahlenther Onkol 188(10):926–932

    Article  CAS  PubMed  Google Scholar 

  • Hirche C, Mrak K, Kneif S, Mohr Z, Slisow W, Hünerbein M et al (2010) Perineal colostomy with spiral smooth muscle graft for neosphincter reconstruction following abdominoperineal resection of very low rectal cancer: long-term outcome. Dis Colon Rectum 53(9):1272–1279. doi:10.1007/DCR.0b013e3181e74c1f

    Article  PubMed  Google Scholar 

  • Hoerske C, Weber K, Goehl J, Hohenberger W, Merkel S (2010) Long-term outcomes and quality of life after rectal carcinoma surgery. Br J Surg 97(8):1295–1303. doi:10.1002/bjs.7105

    Article  CAS  PubMed  Google Scholar 

  • Hofheinz R, Wenz Z, Post S et al (2011) Capecitabine (Cape) versus 5-fluorouracil (5-FU) -based (neo)adjuvant chemoradiotherapy (CRT) for locally advanced rectal cancer (LARC): long-term results of a randomized, phase III trial. J Clin Oncol 29(Suppl.):3504 [abstr.]

    Google Scholar 

  • Horisberger K, Treschl A, Mai S, Barreto-Miranda M, Kienle P, Ströbel P et al (2009) Cetuximab in combination with capecitabine, irinotecan, and radiotherapy for patients with locally advanced rectal cancer: results of a Phase II MARGIT trial. Int Radiat Oncol Biol Phys 74:1487–1493. doi:10.1016/j.ijrobp.2008.10.014

    Article  CAS  Google Scholar 

  • How P, Stelzner S, Branagan G, Bundy K, Chandrakumaran K, Heald RJ et al (2012) Comparative quality of life in patients following abdominoperineal excision and low anterior resection for low rectal cancer. Dis Colon Rectum 55(4):400–406. doi:10.1097/DCR.0b013e3182444fd1

    Article  CAS  PubMed  Google Scholar 

  • Kang SB, Park JW, Jeong SY, Nam BH, Choi HS, Kim DW et al (2010) Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): short-term outcomes of an open-label randomised controlled trial. Lancet Oncol 11(7):637–645. doi:10.1016/S1470-2045(10)70131-5

    Article  PubMed  Google Scholar 

  • Kasparek MS, Hassan I, Cima RR, Larson DR, Gullerud RE, Wolff BG (2011) Quality of life after coloanal anastomosis and abdominoperineal resection for distal rectal cancers: sphincter preservation vs quality of life. Colorectal Dis 13(8):872–877. doi:10.1111/j.1463-1318.2010.02347.x

    Article  CAS  PubMed  Google Scholar 

  • Kasparek MS, Hassan I, Cima RR, Larson DR, Gullerud RE, Wolff BG (2012) Long-term quality of life and sexual and urinary function after abdominoperineal resection for distal rectal cancer. Dis Colon Rectum 55(2):147–154. doi:10.1097/DCR.0b013e31823d2606

    Article  PubMed  Google Scholar 

  • Kilic D, Yalman D, Aksu G, Atasoy BM, Igdem S, Dincbas FO et al (2012) Impact of adjuvant chemoradiotherapy for rectal cancer on the long-term quality of life and late side effects: a multicentric clinical evaluation by the Turkish Oncology Group. Asian Pac J Cancer Prev 13(11):5741–5746

    Article  PubMed  Google Scholar 

  • Konanz J, Herrle F, Weiss C, Post S, Kienle P (2013) Quality of life of patients after low anterior, intersphincteric, and abdominoperineal resection for rectal cancer–a matched-pair analysis. Int J Colorectal Dis 28(5):679–688. doi:10.1007/s00384-013-1683-z

    PubMed  Google Scholar 

  • Kripp M, Wieneke J, Kienle P, Welzel G, Brade J, Horisberger K et al (2012) Intensified neoadjuvant chemoradiotherapy in locally advanced rectal cancer—impact on long-term quality of life. Eur J Surg Oncol 38(6):472–477. doi:10.1016/j.ejso.2012.02.002

    Article  CAS  PubMed  Google Scholar 

  • Krouse RS, Herrinton LJ, Grant M, Wendel CS, Green SB, Mohler MJ et al (2009) Health-related quality of life among long-term rectal cancer survivors with an ostomy: manifestations by sex. J Clin Oncol 27(28):4664–4670. doi:10.1200/JCO.2008.20.9502

    Article  PubMed Central  PubMed  Google Scholar 

  • Laforest A, Bretagnol F, Mouazan AS, Maggiori L, Ferron M, Panis Y (2012) Functional disorders after rectal cancer resection: does a rehabilitation programme improve anal continence and quality of life? Colorectal Dis 14(10):1231–1237. doi:10.1111/j.1463-1318.2012.02956.x

    Article  CAS  PubMed  Google Scholar 

  • Leplege A, Hunt S (1997) The problem of quality of life in medicine. JAMA 278(1):47–50

    Article  CAS  PubMed  Google Scholar 

  • Li J, Chen R, Xu YQ, Wang XC, Zheng S, Zhang SZ et al (2010) Impact of a laparoscopic resection on the quality of life in rectal cancer patients: results of 135 patients. Surg Today 40(10):917–922. doi:10.1007/s00595-009-4156-9

    Article  PubMed  Google Scholar 

  • Loomes G, McKenzie L (1989) The use of QALYs in health care decision making. Soc Sci Med 28(4):299–308

    Article  CAS  PubMed  Google Scholar 

  • Mahjoubi B, Mirzaei R, Azizi R, Jafarinia M, Zahedi-Shoolami L (2012) A cross-sectional survey of quality of life in colostomates: a report from Iran. Health Qual Life Outcomes 10:136. doi:10.1186/1477-7525-10-136

    Article  PubMed Central  PubMed  Google Scholar 

  • Marquis P, Marrel A, Jambon B (2003) Quality of life in patients with stomas: the Montreux study. Ostomy/Wound Manage 49:48–55

    Google Scholar 

  • Mrak K, Jagoditsch M, Eberl T, Klingler A, Tschmelitsch J (2011) Long-term quality of life in pouch patients compared with stoma patients following rectal cancer surgery. Colorectal Dis 13(12):e403–e410. doi:10.1111/j.1463-1318.2011.02740.x

    Article  CAS  PubMed  Google Scholar 

  • National Comprehensive Cancer Network, Inc. (updated) NCCN guidelines version 4.2013: rectal cancer. http://www.nccn.org/professionals/physician_gls/pdf/rectal.pdf

  • Neuman HB, Patil S, Fuzesi S, Wong WD, Weiser MR, Guillem JG et al (2011) Impact of a temporary stoma on the quality of life of rectal cancer patients undergoing treatment. Ann Surg Oncol 18(5):1397–1403. doi:10.1245/s10434-010-1446-9

    Article  PubMed  Google Scholar 

  • Ohigashi S, Hoshino Y, Ohde S, Onodera H (2011) Functional outcome, quality of life, and efficacy of probiotics in postoperative patients with colorectal cancer. Surg Today 41(9):1200–1206. doi:10.1007/s00595-010-4450-6

    Article  PubMed  Google Scholar 

  • Orsini RG, Thong MS, van de Poll-Franse LV, Slooter GD, Nieuwenhuijzen GA, Rutten HJ et al (2013) Quality of life of older rectal cancer patients is not impaired by a permanent stoma. Eur J Surg Oncol 39(2):164–170. doi:10.1016/j.ejso.2012.10.005

    Article  CAS  PubMed  Google Scholar 

  • Osoba D, Rodrigues G, Myles J, Zee B, Pater J (1998) Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol 16(1):139–144

    CAS  PubMed  Google Scholar 

  • Pachler J, Wille-Jørgensen P (2005) Quality of life after rectal resection for cancer, with or without permanent colostomy. Cochrane Database Syst Rev 2. doi:10.1002/14651858.CD004323.pub4

  • Parc Y, Zutshi M, Zalinski S, Ruppert R, Fürst A, Fazio VW (2009) Preoperative radiotherapy is associated with worse functional results after coloanal anastomosis for rectal cancer. Dis Colon Rectum 52(12):2004–2014. doi:10.1007/DCR.0b013e3181beb4d8

    Article  PubMed  Google Scholar 

  • Peng J, Shi D, Goodman KA, Goldstein D, Xiao C, Guan Z et al (2011) Early results of quality of life for curatively treated rectal cancers in Chinese patients with EORTC QLQ-CR29. Radiat Oncol 6:93. doi:10.1186/1748-717X-6-93

    Article  PubMed Central  PubMed  Google Scholar 

  • Planting A, Phang PT, Raval MJ, Brown CJ (2013) Transanal endoscopic microsurgery: impact on fecal incontinence and quality of life. Can J Surg 56(4):243–248

    Article  PubMed Central  PubMed  Google Scholar 

  • Prieto L, Thorsen H, Juul K (2005) Development and validation of a quality of life questionnaire for patients with colostomy or ileostomy. Health Qual Life Outcomes 3(1):62. doi:10.1186/1477-7525-3-62

    Article  PubMed Central  PubMed  Google Scholar 

  • Pucciarelli S, Del Bianco P, Efficace F, Toppan P, Serpentini S, Friso ML et al (2010) Health-related quality of life, faecal continence and bowel function in rectal cancer patients after chemoradiotherapy followed by radical surgery. Support Care Cancer 18(5):601–608. doi:10.1007/s00520-009-0699-y

    Article  PubMed  Google Scholar 

  • Pucciarelli S, Del Bianco P, Efficace F, Serpentini S, Capirci C, De Paoli A et al (2011) Patient-reported outcomes after neoadjuvant chemoradiotherapy for rectal cancer: a multicentre prospective observational study. Ann Surg 253(1):71–77. doi:10.1097/SLA.0b013e3181fcb856

    Article  PubMed  Google Scholar 

  • Rabin R, de Charro F (2001) EQ-5D: a measure of health status from the EuroQol Group. Ann Med 33:337–343

    Article  CAS  PubMed  Google Scholar 

  • Renner K, Rosen HR, Novi G, Hölbling N, Schiessel R (1999) Quality of life after surgery for rectal cancer. Dis Colon Rectum 42(9):1160–1167

    Article  CAS  PubMed  Google Scholar 

  • Riss S, Stremitzer S, Riss K, Mittlböck M, Bergmann M, Stift A (2011) Pelvic organ function and quality of life after anastomotic leakage following rectal cancer surgery. Wien Klin Wochenschr 123(1–2):53–57. doi:10.1007/s00508-010-1514-y

    Article  PubMed  Google Scholar 

  • Ristvedt SL, Trinkaus KM (2009) Trait anxiety as an independent predictor of poor health-related quality of life and post-traumatic stress symptoms in rectal cancer. Br J Health Psychol 14(4):701–715. doi:10.1348/135910708X400462

    Article  PubMed Central  PubMed  Google Scholar 

  • Rockwood TH, Church JM, Fleshman JW, Kane RL, Mavrantonis C, Thorson AG et al (2000) Fecal incontinence quality of life scale: quality of life instrument for patients with fecal incontinence. Dis Colon Rectum 43(1):9–16. doi:10.1007/BF02237236

    Article  CAS  PubMed  Google Scholar 

  • Schmidt C, Daun A, Malchow B, Küchler T (2010) Sexual impairment and its effects on quality of life in patients with rectal cancer. Dtsch Arztebl Int 107(8):123–130. doi:10.3238/arztebl.2010.0123

    PubMed Central  PubMed  Google Scholar 

  • Schumacher M, Olschewski M, Schulgen G (1991) Assessment of quality of life in clinical trials. Stat Med 10(12):1915–1930

    Article  CAS  PubMed  Google Scholar 

  • Sebag-Montefiore D, Stephens RJ, Steel R, Monson J, Grieve R, Khanna S et al (2009) Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC CTG C016): a multicentre randomised trial. Lancet 373:811–820. doi:10.1016/S0140-6736(09)60484-0

    Article  PubMed Central  PubMed  Google Scholar 

  • Serpentini S, Del Bianco P, Alducci E, Toppan P, Ferretti F, Folin M et al (2011) Psychological well-being outcomes in disease-free survivors of mid-low rectal cancer following curative surgery. Psychooncology 20(7):706–714. doi:10.1002/pon.1763

    Article  PubMed  Google Scholar 

  • Spielberger CD, Gorsuch RL, Lushene RE (1970) Manual for the state-trait anxiety inventory. Consulting Psychologists Press, Palo Alto

    Google Scholar 

  • Sprangers MA, Taal BG, Aaronson NK, Te Velde A (1995) Quality of life in colorectal cancer. Dis Colon Rectum 38(4):361–369

    Article  CAS  PubMed  Google Scholar 

  • Sprangers M, Te Velde A, Aaronson N (1999) The construction and testing of the EORTC colorectal cancer-specific quality of life questionnaire module. (QLQ-CR38). Eur J Cancer 35(2):238–247

    Article  CAS  PubMed  Google Scholar 

  • Stephens RJ, Thompson LC, Quirke P, Steele R, Grieve R, Couture J et al (2010) Impact of short-course preoperative radiotherapy for rectal cancer on patients’ quality of life: data from the medical research council CR07/national cancer institute of Canada clinical trials group C016 randomized clinical trial. J Clin Oncol 28(27):4233–4239. doi:10.1200/JCO.2009.26.5264

    Article  PubMed  Google Scholar 

  • Stiggelbout AM, de Haes JC (2001) Patient preference for cancer therapy: an overview of measurement approaches. J Clin Oncol 19(1):220–230

    CAS  PubMed  Google Scholar 

  • Sutherland HJ, Till JE (1993) Quality of life assessments and levels of decision making: differentiating objectives. Qual Life Res 2(4):297–303

    Article  CAS  PubMed  Google Scholar 

  • Theodoropoulos GE, Karantanos T, Stamopoulos P, Zografos G (2013) Prospective evaluation of health-related quality of life after laparoscopic colectomy for cancer. Tech Coloproctol 17(1):27–38. doi:10.1007/s10151-012-0869-7

    Article  CAS  PubMed  Google Scholar 

  • Thong MS, Mols F, Lemmens VE, Rutten HJ, Roukema JA, Martijn H et al (2011) Impact of preoperative radiotherapy on general and disease-specific health status of rectal cancer survivors: a population-based study. Int J Radiat Oncol Biol Phys 81(3):e49–e58. doi:10.1016/j.ijrobp.2010.12.030

    Article  PubMed  Google Scholar 

  • Tiv M, Puyraveau M, Mineur L, Calais G, Maingon P, Bardet E et al (2010) Long-term quality of life in patients with rectal cancer treated with preoperative (chemo)-radiotherapy within a randomized trial. Cancer Radiother 14(6–7):530–534. doi:10.1016/j.canrad.2010.06.017

    Article  CAS  PubMed  Google Scholar 

  • Varpe P, Huhtinen H, Rantala A, Salminen P, Rautava P, Hurme S et al (2011) Quality of life after surgery for rectal cancer with special reference to pelvic floor dysfunction. Colorectal Dis 13(4):399–405. doi:10.1111/j.1463-1318.2009.02165.x

    Article  CAS  PubMed  Google Scholar 

  • Vaughan-Shaw PG, Cheung T, Knight JS, Nichols PH, Pilkington SA, Mirnezami AH (2012) A prospective case-control study of extralevator abdominoperineal excision (ELAPE) of the rectum versus conventional laparoscopic and open abdominoperineal excision: comparative analysis of short-term outcomes and quality of life. Tech Coloproctol 16(5):355–362. doi:10.1007/s10151-012-0851-4

    Article  CAS  PubMed  Google Scholar 

  • Ward WL, Hahn EA, Mo F, Hernandez L, Tulsky DS, Cella D (1999) Reliability and validity of the functional assessment of cancer therapy-colorectal (FACT-C) quality of life instrument. Qual Life Res 8:181–195. doi:10.1016/j.jpainsymman.2004.12.009

    Article  CAS  PubMed  Google Scholar 

  • Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short-form health survey (SF-36): I. Conceptual framework and item selection. Med Care 30(6):473–483

    Article  PubMed  Google Scholar 

  • Ware J Jr, Kosinski M, Keller SD (1996) A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care 34(3):220–233. doi:10.1097/00005650-199603000-00003

    Article  PubMed  Google Scholar 

  • Whistance RN, Conroy T, Chie W, Costantini A, Sezer O, Koller M et al (2009) European organisation for research and treatment of cancer quality of life group. Clinical and psychometric validation of the EORTC QLQ-CR29 questionnaire module to assess health-related quality of life in patients with colorectal cancer. Eur J Cancer 45(17):3017–3026. doi:10.1016/j.ejca.2009.08.014

    Article  CAS  PubMed  Google Scholar 

  • WHO (1946) Preamble to the Constitution of the World Health Organization as adopted by the International Health Conference, New York, 19–22 June, 1946; signed on 22 July 1946 by the representatives of 61 States (Official Records of the World Health Organization, no 2, p 100) and entered into force on 7 April 1948

    Google Scholar 

  • WHOQoL Group (1993) Measuring quality of life: the development of a world health organisation quality of life instrument (WHOQoL). WHO, Geneva

    Google Scholar 

  • Willeke F, Horisberger K, Kraus-Tiefenbacher U, Wenz F, Leitner A, Hochhaus A et al (2007) A phase II study of capecitabine and irinotecan in combination with concurrent pelvic radiotherapy (CapIri-RT) as neoadjuvant treatment of locally advanced rectal cancer. Br J Cancer 96:912–917. doi:10.1038/sj.bjc.6603645

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Yau T, Watkins D, Cunningham D, Barbachano Y, Chau I, Chong G (2009) Longitudinal assessment of quality of life in rectal cancer patients with or without stomas following primary resection. Dis Colon Rectum 52(4):669–677. doi:10.1007/DCR.0b013e31819eb970

    Article  PubMed  Google Scholar 

  • You YN, Habiba H, Chang GJ, Rodriguez-bigas MA, Skibber JM (2011) Prognostic value of quality of life and pain in patients with locally recurrent rectal cancer. Ann Surg Oncol 18(4):989–996. doi:10.1245/s10434-010-1218-6

    Article  PubMed Central  PubMed  Google Scholar 

  • Zutshi M, Hull T, Shedda S, Lavery I, Hammel J (2013) Gender differences in mortality, quality of life and function after restorative procedures for rectal cancer. Colorectal Dis 15(1):66–73. doi:10.1111/j.1463-1318.2012.03075.x

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Surgical Oncological and Gastroenterological Sciences—First Surgical Clinic, University of Padova, Padua, Italy

    Teresa Gavaruzzi, Alessandro Perin & Salvatore Pucciarelli

  2. Department of Developmental Psychology and Socialization, University of Padova, Padua, Italy

    Francesca Giandomenico & Lorella Lotto

  3. Clinical Trials and Biostatistics Unit, Istituto Oncologico Veneto—IRCCS, Padua, Italy

    Paola Del Bianco

Authors
  1. Teresa Gavaruzzi
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  2. Francesca Giandomenico
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  3. Paola Del Bianco
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  4. Lorella Lotto
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  5. Alessandro Perin
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  6. Salvatore Pucciarelli
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Correspondence to Salvatore Pucciarelli .

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Editors and Affiliations

  1. Department of Medical Oncology, Tumor- und Brustzentrum ZeTuP, St. Gallen, Switzerland

    Florian Otto

  2. Caritasklinik St. Theresia, Saarbrücken, Germany

    Manfred P. Lutz

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Gavaruzzi, T., Giandomenico, F., Del Bianco, P., Lotto, L., Perin, A., Pucciarelli, S. (2014). Quality of Life After Surgery for Rectal Cancer. In: Otto, F., Lutz, M. (eds) Early Gastrointestinal Cancers II: Rectal Cancer. Recent Results in Cancer Research, vol 203. Springer, Cham. https://doi.org/10.1007/978-3-319-08060-4_10

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