Regular ArticleBiochemical Assay of Collagen and Elastin in the Normal and Varicose Vein Wall
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2019, EJVES Short ReportsCitation Excerpt :Venous compliance is strongly affected by mechanical vessel wall properties, where collagen and elastin play an important role.2 Several histopathological findings in varicose veins suggest abnormal collagen and elastin content,4,5 with increased collagen to elastin ratio in the lower limb venous vessel wall.6,7 This seems to be in agreement with animal studies showing increased collagen to elastin ratio and stiffness in venous hypertension models.16
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