TY - JOUR T1 - Transcutaneous Carbon Dioxide Treatment Is Capable of Reducing Peripheral Vascular Resistance in Hypertensive Patients JF - In Vivo JO - In Vivo SP - 1555 LP - 1559 DO - 10.21873/invivo.11414 VL - 32 IS - 6 AU - BALÁZS NÉMETH AU - ISTVÁN KISS AU - BELLA AJTAY AU - IVÁN PÉTER AU - ZITA KRESKA AU - ATTILA CZIRÁKI AU - IVÁN G. HORVÁTH AU - ZÉNÓ AJTAY Y1 - 2018/11/01 UR - http://iv.iiarjournals.org/content/32/6/1555.abstract N2 - Aim: We aimed to investigate the effects of a single carbon dioxide (CO2) treatment on arterial stiffness by monitoring the changes of aortic pulse-wave velocity (PWV) and aortic augmentation index (AIXao), which are indicators of arterial stiffness. Patients and Methods: PWV and AIXao were measured by an invasively validated oscillometric device. The measurements of stiffness parameters were performed before the CO2 treatment, and at 1, 4 and 8 h after the first treatment. Results: Thirty-one patients were included. No significant changes were found in PWV. AIXao decreased significantly 1 h and 4 h after CO2 treatment compared to baseline values (p=0.034 and p<0.001). AIXao increased 8 h after the CO2 treatment, but remained significantly lower than baseline AIXao values (p=0.016). Conclusion: CO2 treatment is capable of reducing peripheral vascular resistance. We hypothesize that CO2 is not only a temporal vasodilator but is also capable of activating vasodilation pathways. ER -